Protein Alignment AOX2 and Aox2

DIOPT Version :10

• Sequence 1: NP_732047.2
• Gene: AOX2 / 41895
• FlyBaseID: FBgn0038348
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_063123260.1
• Gene: Aox2 / 316421
• RGDID: 1359668
• Length: 1351
• Species: Rattus norvegicus
• Alignment Length: 1387
• Identity: 403/1387 - (29%)
• Similarity: 630/1387 - (45%)
• Gaps: 216/1387 - (15%)

  Fly     3 IKFNVNGFPYEVQAADYPPDTTLNTFLREH--LHLTATKYMCLEGGCGSCVCVIRRRHPVTQEVQ 65
            ::|.|||  .:|...:..|:.||..|||::  |.||.|||.|..|.||:|..::.:..||.::.:
  Rat    11 LEFFVNG--KKVTEKNVDPEVTLLAFLRKNWTLCLTGTKYACGTGSCGACTVMVSQHDPVCKKTR 73

  Fly    66 SRAANSCLTLLNTCDDAEIMTDEGLGNQLSGYHPIQKRVAQMNGTQCGYCSPGFVMNMYGLLEQH 130
            ..:..:||..|.:...|.:.|.||:|:..:..||:|:|:|:.:|||||:||||.||:||.||..|
  Rat    74 HFSVMACLVPLCSLHGAAVTTVEGVGSIKTRLHPVQERLAKSHGTQCGFCSPGMVMSMYALLRNH 138

  Fly   131 RGQVSMSQVEDAFGGNLCRCTGYRPILDAMKSFAVDSNVEVPAESVDIEDSFELLCPRTGQSC-- 193
             .|.|..|:.:|.||||||||||||||::.::|.::|:              ..|...|||.|
  Rat   139 -PQPSEEQLLEALGGNLCRCTGYRPILESGRTFCMESD--------------GCLQKGTGQCCLD 188

  Fly   194 ------KGS----CSR------------------PP----LRDHGDSQ----------WYWPKTL 216
                  .||    |:.                  ||    :.::.:.|          |..|.||
  Rat   189 QKEGDSSGSKSDICTELFVKDEFQPLDPTQELIFPPELLRMAENPEKQTLTFYGERITWIAPGTL 253

  Fly   217 TELFGALSQVANGELYMLVAGNTAHGVYRRPRDIRHFIDVNM----VPELRQYSIETDHLLLGGN 277
            .||....::.....   |::||||.|...:.:.  ||..|.:    :|:||..:..:..|.:|..
  Rat   254 QELLVLKAKYPEAP---LISGNTALGPAMKSQG--HFYPVLLSPARIPDLRMVTKTSGGLTIGAC 313

  Fly   278 VTLTDAMQVFLLAAKRPGFE----YCAQLWQHFNLIANVPVRNNGTLAGNINIKKQHFEFPSDVF 338
            .:|.....|...:......|    |.| |.:|...:|...:||..:|.|:: |.:.::.
  Rat   314 CSLAQVKDVLAESISELPEEKTQTYRA-LLKHLRSLAGQQIRNMASLGGHV-ISRHYYS------ 370

  Fly   339 ITFEALDVHVLVYDNPSTQRVMNLLTYLG-----------------DTTSKLVLGGFILKAYPKD 386
                  |::.::....:|   :|||:..|                 |...:.:||...:....|.
  Rat   371 ------DLNPILSVGNAT---LNLLSEEGLRQIPLNGHFLAGLANEDLKPEEILGSVYIPHSQKR 426

  Fly   387 RFL--FRSYKILPRAQNVHAYVNAGFLI---EWQDIQHRIVHSARICFGNIRPDYIHDDQVEQLL 446
            .|:  ||..:.   .||....||||..:   |..|    |:....|.:|.:.|..:...:..|.|
  Rat   427 EFVSAFRQAQC---HQNALPDVNAGMRVLFKEGTD----IIEELSIAYGGVGPTTVSAHRSCQQL 484

  Fly   447 PGRD----LYDPATVAQIFQ-ELPASLQPEERPPEASPEYRQMLACSLLYKFLLATAPKERVRER 506
            .||.    |.|.|....:.: .||.|      ......|:|:.|..|..:||.|....:.:..:|
  Rat   485 LGRRWNALLLDEACRLLLDEVSLPGS------AVGGKVEFRRTLIVSFFFKFYLEVLQELKADKR 543

  Fly   507 FRTGGLLLER-----------------PLSSGSQSFETIKKNY----PVTQPVQKLEGLIQCSGE 550
            ........:|                 .|..|.|:::.:..:.    ||.:|:..|.||...:||
  Rat   544 LLPESTDSQRYPEIADGSRSSLGDFQVTLPQGVQTYQRVNSHQPLQDPVGRPIMHLSGLKHATGE 608

  Fly   551 ATYMNDLLTTSNAVHCAFVTAKRVGATIEQIDPSAALQCKGVVAFYSAEDIPGSNNFVLVNQLTP 615
            |.:.:|:......:..|.||:.|..|.|..||.|..|...|||...:||||||:|.        .
  Rat   609 AVFCDDIPRVDKELFMALVTSTRAHARIISIDSSEVLDLPGVVDVITAEDIPGNNG--------E 665

  Fly   616 EVDEVFVAGRVKYFDQPLGVIAALTHDAAVYAATLVVVTYARDQRKIFTTMNQVL-------AEK 673
            |.|::....:|....|.:..:.|.|...|..|...:.:|| .|.:.:..|:...:       .||
  Rat   666 EDDKLLAVDKVLCVGQVVCAVVAETDVQAKRATKKIKITY-EDLKPVLFTIEDAIQHNSFLCPEK 729

  Fly   674 QTDRIVSTKKDTVEPLKLPPLAPGDVLGRGILELASQYHFTMEPQTTIVVPL--DNILQVYCATQ 736
            :.::  ...::..|.:        |.:..|.:.:..|.||.||.|..:|:|.  |..|.:|.:||
  Rat   730 KLEQ--GNMEEAFENV--------DQIVEGKVHVGGQEHFYMETQRVLVIPKTEDKELDMYVSTQ 784

  Fly   737 WMDATQGAIAHMLKVSVNSIQLQVRRVGGAYGAKVTRGNIVACATALVASKLRRPARFVQTIESM 801
            .....|..::..|.:.::.|...|:||||.:|.||.|..:.....|:.|.|..||.|.|...|..
  Rat   785 DPAHVQKTVSSALNIPLSRITCHVKRVGGGFGGKVGRPAVFGAIAAVGAVKTGRPIRLVLDREDD 849

  Fly   802 METIGKRWACRSDYEFRARANGSIIMLSNNYYEDSGCNLNEN--VVDFLTLPILRNVYNLTDANY 864
            |...|.|....:.|:.....:|.|..|....|.:.||.|:::  |.:||.|. |.|.|.:  .|.
  Rat   850 MLITGGRHPLFAKYKVGFMNSGRIKALDIECYINGGCTLDDSELVTEFLVLK-LENAYKI--RNL 911

  Fly   865 RTQGSAIRTDAPSSTWCRAPGSAEGIAMTETALEHIAFTCQLDPADVRLVNL----------QPG 919
            |.:|.|..|:.||:|..|..|..:|..:||:.:..:|..|.|.|..:|..|:          |..
  Rat   912 RLRGRACMTNLPSNTAFRGFGFPQGALVTESCITAVAAKCGLPPEKIREKNMYKTVDKTIYKQAF 976

  Fly   920 N--KMVQLLPKFLASTEYHKRRDQINLFNSQNRWRKRGLGLALMSFPLNTTVAFNYPVTVAIYH- 981
            |  .:::...:.|..:.:..||.:::.||.::.|||||:.:..|.|.:. ..|.:|....|:.|
  Rat   977 NPEPLIRCWNECLDKSSFAIRRTRVDEFNKKSYWRKRGIAVVPMKFSVG-FAATSYHQAAALVHI 1040

  Fly   982 -EDGSVVISHGGIEIGQGVNTKAAQVAAFVLGVPLDQVRVEASNTVNGANSMLTANSMTSEMIGL 1045
             .||||:::|||.|:|||::||..|||:..|.:|:..:....:.|....|::.||.|:.:::.|.
  Rat  1041 YTDGSVLVAHGGNELGQGIHTKMLQVASRELKIPMSYLHTSETCTAAVPNTIATAASVGADVNGR 1105

  Fly  1046 AVRKACDTLNKRLAPVKERLGPRASWVQVLQAAFLQSVFLIATESYR-----------LGDIPNY 1099
            ||:.||..|.|||.||.:: .|..:|...::|||.|.:.|.||..:|           .||...|
  Rat  1106 AVQNACQILLKRLEPVIKK-NPEGTWRDWIEAAFEQRISLSATGYFRGYKAFMDWEKGEGDPFPY 1169

  Fly  1100 NIFGLSLTELELDILTGNHLIRRVDILEDAGESLSPHIDVGQVEGAFVMGLGYYLTEQLVYDRQT 1164
            .::|.:.:|:|:|.|||.|...|.||:.||..||:|.|||||:||||:.|:|.|.||:|.|..:
  Rat  1170 YVYGAACSEVEIDCLTGAHKKMRTDIVMDACCSLNPAIDVGQIEGAFIQGMGLYTTEELHYSPE- 1233

  Fly  1165 GQILTNRTWNYHPPGAKDIPIDFRIELLQKSPNPVGFMRSKATGEPALCLAVGALFAMQHAIQSA 1229
            |.:.:.....|..|...|:|..|.:.||..|..|:....||..||..:.|.....||:..|:.:|
  Rat  1234 GVLYSRSPDKYKIPTVTDVPEQFNVSLLPSSQTPLTIYSSKGLGESGMFLGSSVFFAIADAVAAA 1298

  Fly  1230 RNDAGLPREWVRLGAPTTPETV 1251
            |....:..::. :.:|.|||.|
  Rat  1299 RRQRDIAEDFT-VKSPATPERV 1319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX2	NP_732047.2	PLN02906	24..1251	CDD:215491	396/1364 (29%)
Aox2	XP_063123260.1	None