Protein Alignment AOX2 and LOC100495429

DIOPT Version :10

• Sequence 1: NP_732047.2
• Gene: AOX2 / 41895
• FlyBaseID: FBgn0038348
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_012825683.2
• Gene: LOC100495429 / 100495429
• XenbaseID: XB-GENE-29082699
• Length: 1323
• Species: Xenopus tropicalis
• Alignment Length: 1334
• Identity: 396/1334 - (29%)
• Similarity: 624/1334 - (46%)
• Gaps: 122/1334 - (9%)

  Fly     5 FNVNGFPYEVQAADYPPDTTLNTFLREHLHLTATKYMCLEGGCGSCVCVIRRRHPVTQEVQSRAA 69
            |.|||.....:.||  |:..|..:||:.|.||.|||.|..||||:|..::...|||::::...:|
 Frog    12 FFVNGRKIVEENAD--PEELLLPYLRKKLLLTGTKYGCGGGGCGACTVMVSTIHPVSKKILHFSA 74

  Fly    70 NSCLTLLNTCDDAEIMTDEGLGNQLSGYHPIQKRVAQMNGTQCGYCSPGFVMNMYGLLEQHRGQV 134
            |:||..:.:...|.:.|.||:|:..:..||:|:|:|:.:|:|||:|:||.||::|.||..| .:.
 Frog    75 NACLLPICSMHGAAVTTIEGIGSTTTKLHPVQERIAKAHGSQCGFCTPGMVMSVYSLLRNH-PEP 138

  Fly   135 SMSQVEDAFGGNLCRCTGYRPILDAMKSFA-------VDSN----VEVPAESVD----------- 177
            :|.|:.::.|||||||||||||:|..::|.       |..|    :..| ::||
 Frog   139 TMEQIYESLGGNLCRCTGYRPIVDGCRTFCNKTDCCQVKENGMEKISTP-DTVDNILTGLFKEEQ 202

  Fly   178 ---IEDSFELLCPRTGQSCKGSCSRPPLRDHGDSQWYWPKTLTELFGALSQVANGELYMLVAGNT 239
               ::.:.||:.|..............:...|...|..|.:|.||   |...|......||.|||
 Frog   203 FLPLDPTQELIFPPELLLMDKEKKEKLIFQGGRMTWISPSSLQEL---LQLKATYPKAPLVVGNT 264

  Fly   240 AHGVYRRPRDIRH--FIDVNMVPELRQYSIETDHLLLGGNVTLT---DAMQVFLLAAKRPGFEYC 299
            ..|...:.|.|.|  .|..:.:|||.....:.|.:.:|...:||   :|::..:........:..
 Frog   265 IVGPEMKFRGIFHPVIISPSRIPELNFVIHKDDGITVGAACSLTVLKEALKEVVTQQPEEKTKLF 329

  Fly   300 AQLWQHFNLIANVPVRNNGTLAGNINIKKQHFEF-----PSDVFITFEALDVHVLVYDNPSTQRV 359
            ..|.|....:....:||..:|.|||..:....:.     ..:..:|..|:|        .:.|..
 Frog   330 HALLQQLETLGGPQIRNTASLGGNIISRSPTSDLNPVLAAGNCILTVAAID--------GTRQMP 386

  Fly   360 MNLLTYLGDTTSKLVLGGFILKAYPKDRFLFRSYKILPRAQNVHAYVNAGFLIEWQDIQHRIVHS 424
            ::...:.....::.||....| .|.|....:..::...|.:|....|.||..::::: ...|:..
 Frog   387 LDEAFFAHSLKAEEVLVSVHL-PYSKKGDHYSVFRQAQRRENALPIVTAGMKVQFEE-NTDIIKV 449

  Fly   425 ARICFGNIRPDYIHDDQVEQLLPGRDLYDPATVAQIFQELPASLQPEERPPEASPEYRQMLACSL 489
            .||.:|.:.|..:......|.|.|:. :|...:::..:.:...:......|....|||..|..|.
 Frog   450 IRIFYGGVGPTTVFAKTTCQDLIGKH-WDDHMLSEACRLMVHEITLSPSAPGGMVEYRSTLTISF 513

  Fly   490 LYKFLLATAPKERVRERFRTGGLLLERPLSSGSQSFETI-KKNY--------------PVTQPVQ 539
            .:||.|      .|.:|....|.....  .|...||||: .:|.              |:.:|:.
 Frog   514 FFKFYL------EVLQRLNHMGTHYSD--VSALNSFETLCNENVQLYQDVSSRQSVQDPIGRPIM 570

  Fly   540 KLEGLIQCSGEATYMNDLLTTSNAVHCAFVTAKRVGATIEQIDPSAALQCKGVVAFYSAEDIPGS 604
            ...|:...:|||.|.:|:......:...|||:.:..|.|..:|.|.||...|||...:.||.||:
 Frog   571 HYSGIKHATGEAVYCDDMPCVDGELFLYFVTSTKAHAKIVSLDFSEALAQPGVVDVVTTEDCPGT 635

  Fly   605 NNFVLVNQLTPEV--DEVFVAGRVKYFDQPLGVIAALTHDAAVYAATLVVVTYARDQRKIFTTMN 667
            ...:......|.:  |:|...|::      :..:.|.|...|..||..|.|.|...:..|.|...
 Frog   636 CKSMFEEGEVPLLAKDKVLCVGQI------ICAVLADTPARAKKAAAAVKVVYENLEPVILTIQE 694

  Fly   668 QVLAEKQTDRIVSTKKDTVEPLKLPPLAPGDVLGRGILELASQYHFTMEPQTTIVVPL--DNILQ 730
            .:............:...||    ......|.:..|.:.:..|.||.||.|:..|:|.  |..:.
 Frog   695 AIEHNSFFKPQRKLENGNVE----EAFKSADQIQEGEIYIGGQEHFYMETQSIRVLPKGEDKEMD 755

  Fly   731 VYCATQWMDATQGAIAHMLKVSVNSIQLQVRRVGGAYGAKVTRGNIVACATALVASKLRRPARFV 795
            ||.:||.....|..||.:|.|..|.|...|:|||||:|.|.|:...:|..||:.|:|.||..|.|
 Frog   756 VYVSTQDPTYIQNLIATILNVPSNRITCHVKRVGGAFGGKTTKTGNIAAITAVAANKTRRAVRCV 820

  Fly   796 QTIESMMETIGKRWACRSDYEFRARANGSIIMLSNNYYEDSGCNLNENV-VDFLTLPILRNVYNL 859
            ......|...|.|......|:.....:|.|..:...|:.::||..:::| |..:.|..:.:.|.|
 Frog   821 FERGDDMLITGGRHPFLGKYKVGFMNDGHITAVDVAYFSNAGCTPDDSVLVVEIALMNMDSAYRL 885

  Fly   860 TDANYRTQGSAIRTDAPSSTWCRAPGSAEGIAMTETALEHIAFTCQLDPADVRLVNLQPGNKMVQ 924
              .|.|..|:|.:|:.||:|..|..|..:...:|||.:..:|..|::.|..||.:||........
 Frog   886 --PNVRCTGTACKTNLPSNTAFRGFGYPQAAFVTETWISEVAIKCRIPPEKVREMNLYKDISQTH 948

  Fly   925 LLPKFLAST------------EYHKRRDQINLFNSQNRWRKRGLGLALMSFPLNTTVAFNYPVTV 977
            ...:.||.|            .|:.||..|..||..|.|:|:||.:..|.||:.:...| :....
 Frog   949 FRQEILARTLGMCWNECMEKSSYNSRRLAIENFNKDNYWKKKGLAIIPMKFPIGSLAKF-FGQAA 1012

  Fly   978 AIYH--EDGSVVISHGGIEIGQGVNTKAAQVAAFVLGVPLDQVRVEASNTVNGANSMLTANSMTS 1040
            |:.|  .||||:::|||||:||||:||..|:|:..||:||..:.:..:||.:..|:.::..|:.:
 Frog  1013 ALVHIYLDGSVLVTHGGIEMGQGVHTKIMQIASRELGIPLSYIHICETNTSSVPNTQVSGGSLGT 1077

  Fly  1041 EMIGLAVRKACDTLNKRLAPVKERLGPRASWVQVLQAAFLQSVFLIATESYRL-----------G 1094
            ::.|:||:.||:.|.:||.|::.: .|::||.:.:..|::|||.|.||...|.           |
 Frog  1078 DVNGMAVKNACEILMQRLLPIRSK-NPKSSWKEWVTEAYMQSVSLSATGFCRSFDRELNWETGEG 1141

  Fly  1095 DIPNYNIFGLSLTELELDILTGNHLIRRVDILEDAGESLSPHIDVGQVEGAFVMGLGYYLTEQLV 1159
            :..:|.::|::.:|:|:|.|||:|...|.||:.|.|.|::|.:|:||:|||||.|||.:..|:|.
 Frog  1142 NPVHYCVYGVACSEVEIDCLTGDHKNLRTDIVIDFGCSINPAVDIGQIEGAFVQGLGLFTIEELK 1206

  Fly  1160 YDRQTGQILTNRTWNYHPPGAKDIPIDFRIELLQKSPNPVGFMRSKATGEPALCLAVGALFAMQH 1224
            :. ..|.:.|.....|..|..:|||..|.:.||...||......||..|||||.|.....||::.
 Frog  1207 FS-PNGVLYTRGPAQYKIPSVRDIPEQFNVSLLSNVPNSCAIYSSKGVGEPALFLGSSIYFAIKD 1270

  Fly  1225 AIQSARNDAGLPREWVRLGAPTTPETVVLNSGSQ 1258
            |:.|||.:.|: .|...|.:|.|||.:.:..|.|
 Frog  1271 AVLSARRERGM-SELFTLNSPATPEKIRMACGDQ 1303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX2	NP_732047.2	PLN02906	24..1251	CDD:215491	387/1306 (30%)
LOC100495429	XP_012825683.2	mam_aldehyde_ox	10..1323	CDD:132014	396/1334 (30%)