Protein Alignment AOX2 and aox1

DIOPT Version :9

• Sequence 1: NP_732047.2
• Gene: AOX2 / 41895
• FlyBaseID: FBgn0038348
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_017953036.2
• Gene: aox1 / 100379890
• XenbaseID: XB-GENE-6045207
• Length: 1322
• Species: Xenopus tropicalis
• Alignment Length: 1346
• Identity: 409/1346 - (30%)
• Similarity: 646/1346 - (47%)
• Gaps: 164/1346 - (12%)

  Fly     5 FNVNGFPYEVQAADYPPDTTLNTFLREHLHLTATKYMCLEGGCGSCVCVIRRRHPVTQEVQSRAA 69
            |.|||  .:|...:..|:..|..:||.:||||.|||.|..||||:|..:|...|||::::....|
 Frog    13 FYVNG--RKVVEKNPDPEDMLLPYLRRNLHLTGTKYGCGGGGCGACTVMISTVHPVSKKIIHYPA 75

  Fly    70 NSCLTLLNTCDDAEIMTDEGLGNQLSGYHPIQKRVAQMNGTQCGYCSPGFVMNMYGLLEQHRGQV 134
            .:||..:.:.....:.|.||:||..:..||:|:|:|:.:|:|||:|:||.||::|.||..| .:.
 Frog    76 LACLLPICSLYGNAVTTTEGIGNSTTKLHPVQERIAKAHGSQCGFCTPGMVMSIYTLLRNH-PEP 139

  Fly   135 SMSQVEDAFGGNLCRCTGYRPILDAMKSFAVDSNVEVPAES-----------------VDIEDSF 182
            :|.|:..|..||||||||||||||..|:|:.|..:....|.                 :.::.:.
 Frog   140 TMEQILSALSGNLCRCTGYRPILDGCKTFSKDCCLNEKKEHRLEEVKSFPKLFYEKDFLPLDPTQ 204

  Fly   183 ELLCPRTGQSCKGSCSRPPLRDHGDSQ------------WYWPKTLTELFGALSQVANGELYMLV 235
            :|:.|            |.|....:||            ||.|.||.|:....::..:..   ||
 Frog   205 DLIFP------------PELMMMFNSQKKMNVFLGERITWYSPSTLDEILELKTKYPSAP---LV 254

  Fly   236 AGNTAHGVYRRPRDIRHFIDVNMVPELRQYSIETDH--LLLGGNVTLTDAMQVF---LLAAKRPG 295
            .||||.|...:.:.:.|.:.::.|..:..|::..:.  :.:|...:|:...::.   :.|.:...
 Frog   255 VGNTALGPQMKFQGVIHPVLISPVRVMDLYNVSLNDMGISIGAACSLSQVKEILCENISAIQEDK 319

  Fly   296 FEYCAQLWQHFNLIANVPVRNNGTLAGNINIKKQHFEFPSDVFITFEALDVHVLVYDNPSTQRV- 359
            .:....|.||...:|...:|:..::.|:| |.|:..   ||:.....|....:.......|::|
 Frog   320 AKIFHALLQHLGTLAGEQIRSMASIGGHI-ISKRTI---SDLNPILAAGGAILNFASKGETRQVE 380

  Fly   360 MNLLTYLGDTTSK---LVLGGFILKAYPKDRFLFRSYKILPRAQNVHAYVNAGFLIEWQDIQHRI 421
            :|.|.:.|.:..|   ::|..||..: .||.|: .:::...|.:|.:|.||||..:.::: ...|
 Frog   381 LNELFFTGSSPQKSEEVLLSVFIPYS-KKDEFV-SAFRQAQRDENANAIVNAGMKVHFEE-DTDI 442

  Fly   422 VHSARICFGNIRPDYIHDDQVEQLLPGRDLYDPATVAQ----IFQELPASLQPEERPPEASPEYR 482
            |....|.:|.:.|..::.....|.|.||. :|...:.:    |.:|:  :|.|.  .|....:||
 Frog   443 VKEMAIYYGCMGPSTVYAKNTSQALIGRH-WDEEMLNEACKLILEEI--TLSPS--APGGKVQYR 502

  Fly   483 QMLACSLLYKFLLATAPKERVRERFRTGGLLLERPLSSGS--------------------QSFET 527
            :.|..|..:||.|....             .|::.:.|.|                    |.|:.
 Frog   503 RALTISFFFKFYLQVLQ-------------CLKKTIKSSSVASDYISAIKDFEINTPKTLQIFQE 554

  Fly   528 IKKNYPVTQPV----QKLEGLIQCSGEATYMNDLLTTSNAVHCAFVTAKRVGATIEQIDPSAALQ 588
            .::..|:..||    ....|:.|.:|||.|::|:.|....:..||||:||..|.|..||.|.||.
 Frog   555 TEQEQPIDDPVGHPIVHTSGIKQATGEAIYVDDMPTVDQELFIAFVTSKRAHAKILSIDASEALA 619

  Fly   589 CKGVVAFYSAEDIPGSNNFVLVNQLTPEVDEVFVAGRVKYFDQPLGVIAALTHDAAVYAATLVVV 653
            ..||.....||||||.|....:|.|..| |:|...|::      :..:.|.|...|..||..|.:
 Frog   620 LPGVCDIIRAEDIPGKNELDGLNHLFSE-DKVECVGQI------ICAVVADTPKHAKQAAAKVKI 677

  Fly   654 TYARDQRKIFTTMNQVLAEKQTDRIVSTKKDTVEPLKLPPLAPGDVLGRGILELASQYHFTMEPQ 718
            .| ::...:..||...:   :.:.....:|..:...........|.:..|.:.:..|..|.||..
 Frog   678 DY-QNLEPVILTMEDAI---KNNSFFEPEKKIIHGNAEEAFKSADHILEGEVHIGGQEQFYMETN 738

  Fly   719 TTIVVPL--DNILQVYCATQWMDATQGAIAHMLKVSVNSIQLQVRRVGGAYGAKVTRGNIVACAT 781
            |.:|||.  :|.|.:|.:||.....|.|:|..|.|..|.:...|:|||||:|.|:|:.:|.|||:
 Frog   739 TVLVVPKGEENELDIYVSTQDPTGVQLAVAACLNVPSNRVMCHVKRVGGAFGGKITKPSIFACAS 803

  Fly   782 ALVASKLRRPARFV-QTIESMMETIGKRWACRSDYEFRARANGSIIMLSNNYYEDSGCNLNENVV 845
            |:.|.|.:||.|.| :..|.|:.|.| |......|:.....:|.|:.|..::|.::||:.:|:::
 Frog   804 AVAAHKTKRPVRCVLERGEDMLITAG-RHPFFGKYKVGFMNDGRIVGLDVSFYTNAGCSTDESIL 867

  Fly   846 DFLTLPILR--NVYNLTDANYRTQGSAIRTDAPSSTWCRAPGSAEGIAMTETALEHIAFTCQLDP 908
             .|.:.:::  |.|:.  .|.....:|.:|:.||:|..|..|..:...:|||.::.:|..|.|.|
 Frog   868 -VLVVALIKMDNAYHF--PNLTCTATACKTNLPSNTAFRGFGFPQTGLVTETIMDAVAVKCGLQP 929

  Fly   909 ADVRLVNLQPG------------NKMVQLLPKFLASTEYHKRRDQINLFNSQNRWRKRGLGLALM 961
            ..||..|:..|            ..:::...:.:..:.|..|||.|..||.:|.|:|:|:.:
 Frog   930 HQVREKNMYTGIGKTHYNQEFDSTNLMRCWNECMQKSSYQSRRDAIQEFNKENYWKKKGIAI--- 991

  Fly   962 SFPLNTTVAF---NYPVTVAIYH--EDGSVVISHGGIEIGQGVNTKAAQVAAFVLGVPLDQVRVE 1021
             .||..||.|   .|....|:.|  .||.|::||.|:|:|||:.||..||.:..|.:|:..:.:.
 Frog   992 -IPLKFTVGFVEKTYHQAAALVHIYRDGYVLVSHSGVEMGQGLYTKIVQVVSRELKIPMSYIYIC 1055

  Fly  1022 ASNTVNGANSMLTANSMTSEMIGLAVRKACDTLNKRLAPVKERLGPRASWVQVLQAAFLQSVFLI 1086
            .::||...||:.:..|:.:::.|:||:.|||.|.:||.|:..| .|...|.:.:..||.|.:.|.
 Frog  1056 ETSTVTVPNSIASGGSIGTDITGIAVKNACDILQQRLEPIISR-NPNGKWEEWVSEAFEQRISLS 1119

  Fly  1087 ATESYR-----------LGDIPNYNIFGLSLTELELDILTGNHLIRRVDILEDAGESLSPHIDVG 1140
            :|..||           .|....|.|||.:.:|:|||.|||.:...|.||:.|.|:|::|.||:|
 Frog  1120 STGYYRGYDTYMDWEKGEGHAGPYYIFGAACSEIELDCLTGKYNNLRTDIVMDLGQSINPGIDIG 1184

  Fly  1141 QVEGAFVMGLGYYLTEQLVYDRQTGQILTNRTWNYHPPGAKDIPIDFRIELLQKSPNPVGFMRSK 1205
            ||||||..|.|.|.||:|.|. ..|.:.|.....|..|...|||.:|.:.||..|.||.....||
 Frog  1185 QVEGAFTQGFGLYTTEELQYS-PFGSLYTLGPDKYIMPAVCDIPREFNVYLLASSNNPYTIYSSK 1248

  Fly  1206 ATGEPALCLAVGALFAMQHAIQSARNDAGLPREWVRLGAPTTPETV 1251
            ..||.||.|.....||::.||.|||.:.||.:::. |.:|..||.:
 Frog  1249 GVGETALFLGCSVFFAIKDAIDSARAERGLSKDFT-LNSPAGPERI 1293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX2	NP_732047.2	fer2	3..84	CDD:238126	29/78 (37%)
		PLN02906	24..1251	CDD:215491	403/1325 (30%)
		Fer2_2	86..159	CDD:280048	39/72 (54%)
		FAD_binding_4	206..366	CDD:303082	37/177 (21%)
		CO_deh_flav_C	391..497	CDD:281449	29/109 (27%)
		Ald_Xan_dh_C	548..655	CDD:214971	40/106 (38%)
		Ald_Xan_dh_C2	702..1184	CDD:280834	175/514 (34%)
aox1	XP_017953036.2	mam_aldehyde_ox	11..1320	CDD:132014	409/1346 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D48717at2759
OrthoFinder	1	1.000	-	-		FOG0000201
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010