Protein Alignment AOX1 and xdhA

DIOPT Version :10

• Sequence 1: NP_650475.1
• Gene: AOX1 / 41894
• FlyBaseID: FBgn0267408
• Length: 1273
• Species: Drosophila melanogaster
• Sequence 2: NP_417342.1
• Gene: xdhA / 947116
• ECOCYCID: G7485
• Length: 752
• Species: Escherichia coli
• Alignment Length: 800
• Identity: 193/800 - (24%)
• Similarity: 324/800 - (40%)
• Gaps: 150/800 - (18%)

  Fly   549 EGLIQCSGEATYSNDLPTQHNQLWAAFVIAKKVGAKV-----TKVDTQPALDLPGVVAYLDAKDI 608
            :.:.:.:|.|.|::|      .:.|....||.|.:.:     ..::.:.|..||||:|....:|:
E. coli     4 DAIAKVTGRARYTDD------YVMAGMCYAKYVRSPIAHGYAVSINDEQARSLPGVLAIFTWEDV 62

  Fly   609 PGPNY--------VGPKIRDQFFFPKDEELFATGEIKFYGQPVGIILANSNSLANRAAELVKLTY 665
            |...:        :....||    ..|..|. |..::.:|..|.|::|.....|.:||:||.:.:
E. coli    63 PDIPFATAGHAWTLDENKRD----TADRALL-TRHVRHHGDAVAIVVARDELTAEKAAQLVSIEW 122

  Fly   666 EGGAEEILPSLKAVLDKVGSEAGNNKRLEQPIKSTIDVLQLEEPFDVSSSGQLDMGLQYHYYMEP 730
            :.......|......|......|.| .|:|...||.:|.|..:..|....|.....:..|.:||.
E. coli   123 QELPVITTPEAALAEDAAPIHNGGN-LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMES 186

  Fly   731 QTTVV-LPFEGGLQVYAATQWMDLTQDTIANVLNLKSNDVQVKTRRIGGGYGGKATRCNLAAAAA 794
            .|::. :..:..:.:.::||...:.:..:...|::..:.|:|....:|||:|.|  :..|....|
E. coli   187 VTSLAWMEDDSRITIVSSTQIPHIVRRVVGQALDIPWSCVRVIKPFVGGGFGNK--QDVLEEPMA 249

  Fly   795 ALAAHKLNR-PIRFVQSLESIMTSLGKRWAFHCDYDFFVQKSGKISGIVSRFYEDAGYLANESPI 858
            |....||.. |::...|.|....:...|.||..|....|.:.|.:.|.......:.|..|:.
E. coli   250 AFLTSKLGGIPVKVSLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASH--- 311

  Fly   859 GHTV------------------LLSKNCYEFSDNYKLDGYLVCTDSPSNTPCRAPGSVEGIAMME 905
            ||::                  ..||.||              |:.||....|..|:.:.:..:|
E. coli   312 GHSIASAGGNKVAYLYPRCAYAYSSKTCY--------------TNLPSAGAMRGYGAPQVVFAVE 362

  Fly   906 NIIEHIAFETGVDPADVRFANLLPAHKMGDM------------MPRFLESTK----YRERKAEAI 954
            ::::..|...|:||.::|..|   |.:.||.            :|..||..:    :.:|:||
E. coli   363 SMLDDAATALGIDPVEIRLRN---AAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAE-- 422

  Fly   955 AHNKENRWHKRGLGLCIMEYQIGYFGQYPATVAI------YHSDGTVVVSHGGIEMGQGMNTKIS 1013
            ..|::... :||:|:....|.   ...:|..|.|      .:.|||:.|..|..|:|||.:|..|
E. coli   423 CQNQQGNL-RRGVGVACFSYT---SNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFS 483

  Fly  1014 QVAAHTLGIPMEQVRIEASDTINGANSMVT---GGAVGSE---TLCFAVRKACETLNER------ 1066
            |:.|.|:|:|:..||:     |:..::.||   .||..|.   ....|:|.|...|.|:
E. coli   484 QMVAETVGVPVSDVRV-----ISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAA 543

  Fly  1067 ---------LKPVREEV----KPE----NWQDLIQEAY---NRKINLIASDQCKQGDMDPYSVCG 1111
                     |..::..:    :||    :.:||..:|:   .|...|.|....|.....|  ..|
E. coli   544 VMLHQSAMNLTLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPP--AFG 606

  Fly  1112 LCLTEVELDVLTGNYIVGRVDILEDTGESLNPNVDIGQIEGAFMMGLGYWTSEQVIADPKTGECL 1176
            ....::.:|:......:.|:..:.|:|..|||.:..||:.|...||:|:...|::|.|.|:|...
E. coli   607 CTFVDLTVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGVVR 671

  Fly  1177 TNRTWTYKPPGAKDIP--TDLRIELLPKSPNKAGFMRSKATGEPAICLSIAVAFALQQALQSARD 1239
            ......||.|...|:|  ....:|:  ..|..|  ...|:.|||.|   |.||.|::.|::.|
E. coli   672 NPNLLDYKMPTMPDLPQLESAFVEI--NEPQSA--YGHKSLGEPPI---IPVAAAIRNAVKMA-- 727

  Fly  1240 DAGVPKSWVTLTAPMTPEHL 1259
             .||..:    |.|:||:.|
E. coli   728 -TGVAIN----TLPLTPKRL 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX1	NP_650475.1	PLN02906	28..1259	CDD:215491	192/798 (24%)
xdhA	NP_417342.1	PRK09970	1..752	CDD:236637	192/799 (24%)