Protein Alignment AOX1 and LOC5667133

DIOPT Version :10

• Sequence 1: NP_650475.1
• Gene: AOX1 / 41894
• FlyBaseID: FBgn0267408
• Length: 1273
• Species: Drosophila melanogaster
• Sequence 2: XP_061505527.1
• Gene: LOC5667133 / 5667133
• VectorBaseID: AGAMI1_015115
• Length: 1291
• Species: Anopheles gambiae
• Alignment Length: 1287
• Identity: 618/1287 - (48%)
• Similarity: 864/1287 - (67%)
• Gaps: 39/1287 - (3%)

  Fly     6 TINGTSHEVNLSALPADISLNTFIREYAGLTGTKFMCQEGGCGVCVCTLTGIHPETGELRTWAVN 70
            ||||..:.|:...:..|.|||||||.:|.||||||||.|||||.||..:.|:||.|.|.::||||
Mosquito    25 TINGKPYTVDAGKISVDTSLNTFIRNHAQLTGTKFMCLEGGCGACVVNVNGLHPVTKEKKSWAVN 89

  Fly    71 SCLTLLNTCLGLEVTTSEGLGNKRVGYHAIQQRLAKMNGTQCGYCSPGIVMNMYGLLKSKGGKVT 135
            |||..:..|.||:|.|.||:||::.|||.||||||.:|||||||||||:|||||.|:::..|.::
Mosquito    90 SCLFPIYACHGLDVLTVEGIGNRKDGYHPIQQRLAHLNGTQCGYCSPGMVMNMYSLMEANRGSIS 154

  Fly   136 MEEVENSFGGNICRCTGYRPILDAMKSFAVDSNIQVPAECIDIEDLSTKKCPKTGQTCSGSCKKQ 200
            ||:|||:|||||||||||||||||.||.|||::.::...|.||||| ||.|||||..|:|.|...
Mosquito   155 MEDVENAFGGNICRCTGYRPILDAFKSLAVDADEKLLDACQDIEDL-TKTCPKTGSACAGKCPSA 218

  Fly   201 QPKGSQ------LYPDGSRWSWPVSLGDLFAALQGAVKEKL---PYMLVAGNTAHGVYRRSPDIK 256
            :.:...      ::.|...|.....:.|:|     |:.|::   ||||||||||||||||||.::
Mosquito   219 RDRAEAKRPVRLVFEDAKEWHRVSQVADIF-----AIFEQIGTKPYMLVAGNTAHGVYRRSPSLQ 278

  Fly   257 AFIDVSGLAELKGHKLSADNSSLTLGGNLSLSETMELCRQLEN-TKGFEYLSQVWQHLDWIANVP 320
            .|||::.:.||..|.:|  ||.|.:|.::||:|.|::.....| :..|.|..|:.:|:|.|||||
Mosquito   279 VFIDINAVEELHTHSVS--NSELVVGASVSLTEFMQILDTAANKSPNFAYCKQLEKHIDLIANVP 341

  Fly   321 VRNAGTLAGNLSIKHAHPEFPSDVFIVLEALDAQVIVQEAVDKQQTVSLASYLGSSMEGKIIRGL 385
            ||||||:|||||||:.|.|||||::::|||:.|::.:.||..|...:|.:.::...|:.|:::.:
Mosquito   342 VRNAGTIAGNLSIKNQHHEFPSDMYLILEAVGAKLTLVEAGGKTSLISPSEFVQLDMQKKLLKSV 406

  Fly   386 VLRAYPKERFAFDSYKIMPRAQNAHAYVNAAFLVEFTADA-KVKSARICFGGIHPEFVHATAIEN 449
            .|.|.....:.|.|:|:|||:||||||||.|||.:|..|: .|:|.|||||||:|||.||||.|:
Mosquito   407 TLPALDGTHYVFRSFKVMPRSQNAHAYVNGAFLTKFAEDSVTVESIRICFGGINPEFTHATATES 471

  Fly   450 LIRDKNPFENGLVEKAFGQLSTLLQPDAVLPDASPVYRRKLACGLFYKFLLKIAAQRKQGLGSRF 514
            .:..||.|:...::....|||..::||.||||||..||:.||..|:||:||.:|......:...|
Mosquito   472 FLVGKNLFDAETIQATMNQLSNEIRPDWVLPDASSEYRKNLAMALYYKYLLNVAPDGTVLVKPSF 536

  Fly   515 VTGGSLLKRPVSSGQQSFETFQEHYPVTKATEKHEGLIQCSGEATYSNDLPTQHNQLWAAFVIAK 579
            .:||::|:||:|||||||:|::.::|:||...|.|.|.|.||||.::||||.|..:|:||||||.
Mosquito   537 RSGGTVLERPLSSGQQSFDTYERNWPLTKNIPKIEALAQTSGEAKFTNDLPVQPGELYAAFVIAT 601

  Fly   580 KVGAKVTKVDTQPALDLPGVVAYLDAKDIPGP-NYVGPKIRDQFFFPKDEELFATGEIKFYGQPV 643
            |...::.|:|...||..|||||:..||||||. |::...:.:|    :.||:|.:||:.::||||
Mosquito   602 KPHTRIGKIDATDALKYPGVVAFYSAKDIPGTNNFMPASLGNQ----EVEEIFCSGEVLYHGQPV 662

  Fly   644 GIILANSNSLANRAAELVKLTYE--GGAEEILPSLKAVLD-----KVGSEAGNNKRLEQPIKSTI 701
            |:|:|.:.:.||.||.||.:.||  ...:.|.|:||:::|     ::..|.....|.....:..:
Mosquito   663 GVIVAETFNQANHAATLVNILYERITQPQPIYPTLKSLVDNQTKTRIFDEPATTTRRGSSYRVKV 727

  Fly   702 DVLQLEEPFDVSSSGQLDMGLQYHYYMEPQTTVVLPFEGGLQVYAATQWMDLTQDTIANVLNLKS 766
            ...:       ..:|:.:|..||||.||.||.|.:|.|.|:.|:::|||:||.|..||::|.:..
Mosquito   728 SAAR-------KVTGRFEMAGQYHYTMETQTCVCVPIEDGMDVHSSTQWVDLCQVAIASMLKVPE 785

  Fly   767 NDVQVKTRRIGGGYGGKATRCNLAAAAAALAAHKLNRPIRFVQSLESIMTSLGKRWAFHCDYDFF 831
            |.:....||:|||||.|.:|....|.|.|||||..|||:|||.::||.|:|:|||:....||:..
Mosquito   786 NSLNFTVRRLGGGYGSKISRAGQIACACALAAHLQNRPVRFVLTIESNMSSIGKRYGCIADYEVD 850

  Fly   832 VQKSGKISGIVSRFYEDAGYLANESPIGHTVLLSKNCYEFSDNYKLDGYLVCTDSPSNTPCRAPG 896
            |:.:|:...:.:.:.:|.|...|||....|.....|||: :..:|:.|....||:||||.|||||
Mosquito   851 VESNGRFVKLTNNYMQDYGASLNESVGEATSEFFNNCYD-TKTWKVVGKAAKTDAPSNTWCRAPG 914

  Fly   897 SVEGIAMMENIIEHIAFETGVDPADVRFANLLPAHKMGDMMPRFLESTKYRERKAEAIAHNKENR 961
            :.|||||:|||:||:|:|.|:||.::|.||:....||.:::|:|....:|.:|||.....|.:||
Mosquito   915 TTEGIAMIENIMEHVAWELGLDPLELRLANMPEGSKMRELLPQFRADVEYNQRKAAIDQFNVDNR 979

  Fly   962 WHKRGLGLCIMEYQIGYFGQYPATVAIYHSDGTVVVSHGGIEMGQGMNTKISQVAAHTLGIPMEQ 1026
            |.|||:.:.:|.|.:||||...|.|||:..||:|.|:|||||||||||||.:||||:.||:|:|:
Mosquito   980 WRKRGIAISLMRYPLGYFGALHALVAIHAGDGSVSVTHGGIEMGQGMNTKAAQVAAYVLGLPLEK 1044

  Fly  1027 VRIEASDTINGANSMVTGGAVGSETLCFAVRKACETLNERLKPVREEVKPENWQDLIQEAYNRKI 1091
            :.|:.:.::...|::||||::.||.:|:||:||||.|.||:||||:..|...|:.:.|..|...:
Mosquito  1045 ISIKPTTSLTSPNAIVTGGSMTSEAVCYAVKKACEILLERIKPVRDAHKDAPWETVTQLCYAGNV 1109

  Fly  1092 NLIASDQCKQGDMDPYSVCGLCLTEVELDVLTGNYIVGRVDILEDTGESLNPNVDIGQIEGAFMM 1156
            :|.|:.|.:..::.||.:.||...|||:||||||..:.||||||||||||:|.:|:|||||||:|
Mosquito  1110 DLCATYQYRATELKPYIIWGLSCAEVEVDVLTGNVQLRRVDILEDTGESLSPGIDVGQIEGAFIM 1174

  Fly  1157 GLGYWTSEQVIADPKTGECLTNRTWTYKPPGAKDIPTDLRIELLPKSPNKAGFMRSKATGEPAIC 1221
            |:|||.:|.::.:.:.|..|||||||||||||||||.|.|:..|.||.|.||.:|||||||||:.
Mosquito  1175 GVGYWLTEALVYNAEDGALLTNRTWTYKPPGAKDIPVDFRVRFLQKSSNPAGVLRSKATGEPALN 1239

  Fly  1222 LSIAVAFALQQALQSARDDAGVPKSWVTLTAPMTPEHLVLHSGTEPSQFKLN 1273
            :||.|.|||:.||:|||.|||:...|:::....||:.:.|.:|....|:|||
Mosquito  1240 MSIVVLFALRNALRSARKDAGLADDWISMGTASTPDQVHLLAGNSIEQYKLN 1291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX1	NP_650475.1	PLN02906	28..1259	CDD:215491	602/1249 (48%)
LOC5667133	XP_061505527.1	None