Protein Alignment AOX1 and ry

DIOPT Version :10

• Sequence 1: NP_650475.1
• Gene: AOX1 / 41894
• FlyBaseID: FBgn0267408
• Length: 1273
• Species: Drosophila melanogaster
• Sequence 2: NP_524337.1
• Gene: ry / 41605
• FlyBaseID: FBgn0003308
• Length: 1335
• Species: Drosophila melanogaster
• Alignment Length: 1340
• Identity: 430/1340 - (32%)
• Similarity: 653/1340 - (48%)
• Gaps: 164/1340 - (12%)

  Fly    22 DISLNTFIREYAGLTGTKFMCQEGGCGVCVCTLTGIHPETGELRTWAVNSCLTLLNTCLGLEVTT 86
            :.:|.||:||...|.|||..|.|||||.|...::.:.....::|..|||:|||.:.:..|..|||
  Fly    23 ECTLLTFLREKLRLCGTKLGCAEGGCGACTVMVSRLDRRANKIRHLAVNACLTPVCSMHGCAVTT 87

  Fly    87 SEGLGNKRVGYHAIQQRLAKMNGTQCGYCSPGIVMNMYGLLKSKGGKVTMEEVENSFGGNICRCT 151
            .||:|:.:...|.:|:||||.:|:|||:|:|||||:||.||:: ..:.:|.::|.:|.||:||||
  Fly    88 VEGIGSTKTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRN-AEQPSMRDLEVAFQGNLCRCT 151

  Fly   152 GYRPILDAMKSFAVDSNIQVPAECIDIEDLSTKKCPKTGQTCSGSCKKQQ-----PKGSQLYP-- 209
            ||||||:..|:|..:....:..:|..:   |.|.|....:|.....::.:     |....::|
  Fly   152 GYRPILEGYKTFTKEFACGMGEKCCKV---SGKGCGTDAETDDKLFERSEFQPLDPSQEPIFPPE 213

  Fly   210 ----------------DGSRWSWPVSLGDLFAALQGAVKEKLP-YMLVAGNTAHGVYRRSPDIKA 257
                            |...|..|.:|.:|   ||  :|.|.| ..||.|||..||   ....|.
  Fly   214 LQLSDAFDSQSLIFSSDRVTWYRPTNLEEL---LQ--LKAKHPAAKLVVGNTEVGV---EVKFKH 270

  Fly   258 FI--------DVSGLAELKGHKLSADNSSLTLGGNLSLSETMELCRQL------ENTKGFEYLSQ 308
            |:        .|..|.|:|     .:...:..|..:||.|...|.||.      ..|:.|:....
  Fly   271 FLYPHLINPTQVKELLEIK-----ENQDGIYFGAAVSLMEIDALLRQRIEQLPESETRLFQCTVD 330

  Fly   309 VWQHLDWIANVPVRNAGTLAGNLSIKHAHPEFPSDVFIVLEALDAQVIVQEAVD---KQQTVSLA 370
            :   |.:.|...:||...|.||  |....|  .||:..||.|..||:.|...||   ::::|.:.
  Fly   331 M---LHYFAGKQIRNVACLGGN--IMTGSP--ISDMNPVLSAAGAQLEVASFVDGKLQKRSVHMG 388

  Fly   371 S-----YLGSSMEG-KIIRGLVLRAYPKERFAFDSYKIMPRAQNAHAYVNAAFLVEFTADAK-VK 428
            :     |..:.:|. :::.|:..|....:::.. ::|...|..:..|.||||..|.|...:. |.
  Fly   389 TGFFTGYRRNVIEAHEVLLGIHFRKTTPDQYIV-AFKQARRRDDDIAIVNAAINVRFEEKSNIVA 452

  Fly   429 SARICFGGIHPEFVHATAIENLIRDKNPFENGLVEKAFGQLSTLLQPDAVLPDASPVYRRKLACG 493
            ...:.|||:.|..|.|.....|:..:. :.:.|||:....|.|.|...|..|.....|||.|...
  Fly   453 EISMAFGGMAPTTVLAPRTSQLMVGQE-WSHQLVERVAESLCTELPLAASAPGGMIAYRRALVVS 516

  Fly   494 LFYKFLLKIAAQRKQGLGSRFVTGGSLLKRPVSSGQQSFETFQEHYPVTKATEKHE--------- 549
            ||:|..|.|:.:    |....:|....|.....||.::|     |.||.|:.:..|
  Fly   517 LFFKAYLAISLK----LSKSGITSSDALPSEERSGAETF-----HTPVLKSAQLFERVCSDQPIC 572

  Fly   550 -----------GLIQCSGEATYSNDLPTQHNQLWAAFVIAKKVGAKVTKVDTQPALDLPGVVAYL 603
                       .|.|.:|||.|::|:|....:::.|||::.|..||:||:|...||.|.||..:.
  Fly   573 DPIGRPKVHAAALKQATGEAIYTDDIPRMDGEVYLAFVLSTKPRAKITKLDASEALALDGVHQFF 637

  Fly   604 DAKDI-PGPNYVGPKIRDQFFFPKDEELFATGEIKFYGQPVGIILANSNSLANRAAELVKLTYEG 667
            ..||: ...|.|||...       ||.:||.||:..|||.||.|.|::.:||.|||.|||:.|
  Fly   638 CYKDLTEHENEVGPVFH-------DEHVFAAGEVHCYGQIVGAIAADNKALAQRAARLVKVEY-- 693

  Fly   668 GAEEILPSLKAVLDKVGSEAGNNKRLEQPIKSTIDVLQLEEPF---DVSSSGQLDMGLQYHYYME 729
              ||:.|.:..:     .:|..:|.........:....:||..   |.:..|...||.|.|:|:|
  Fly   694 --EELSPVIVTI-----EQAIEHKSYFPDYPRFVTKGNVEEALAQADHTFEGTCRMGGQEHFYLE 751

  Fly   730 PQTTVVLPFEGG-LQVYAATQWMDLTQDTIANVLNLKSNDVQVKTRRIGGGYGGKATRCNLAAAA 793
            ....:.:|.:.. |:::.:||.....|..:|:|..|.::.|..:.:|:|||:|||.:|....|..
  Fly   752 THAALAVPRDSDELELFCSTQHPSEVQKLVAHVTALPAHRVVCRAKRLGGGFGGKESRGISVALP 816

  Fly   794 AALAAHKLNRPIRFVQSLESIMTSLGKRWAFHCDYDFFVQKSGKISGIVSRFYEDAGYL--ANES 856
            .||||:::.||:|.:...:..|...|.|..|...|.....|.|.|:......|.:||:.  .:.|
  Fly   817 VALAAYRMGRPVRCMLDRDEDMLITGTRHPFLFKYKVGFTKEGLITACDIECYNNAGWSMDLSFS 881

  Fly   857 PIGHTVLLSKNCYEFSDNYKLDGYLVCTDSPSNTPCRAPGSVEGIAMMENIIEHIAFETGVDPAD 921
            .:...:...:|||.. .|.::.|::..|:.||||..|..|..:|:...|:||..:|...|.|..|
  Fly   882 VLERAMFHFENCYRI-PNVRVGGWVCKTNLPSNTAFRGFGGPQGMYAGEHIIRDVARIVGRDVVD 945

  Fly   922 VRFANLLPAHKMGD------MMPRF---------LESTKYRERKAEAIAHNKENRWHKRGLGLCI 971
            |...|.   :|.||      .:..|         |:.::|.|::.|....|:||||.|||:.:..
  Fly   946 VMRLNF---YKTGDYTHYHQQLEHFPIERCLEDCLKQSRYDEKRQEIARFNRENRWRKRGMAVVP 1007

  Fly   972 MEYQIGY----FGQYPATVAIYHSDGTVVVSHGGIEMGQGMNTKISQVAAHTLGIPMEQVRIEAS 1032
            .:|.|.:    ..|..:.:.|| .||:|::||||:|:|||:|||:.|.||..||||.|.:.|..:
  Fly  1008 TKYGIAFGVMHLNQAGSLINIY-GDGSVLLSHGGVEIGQGLNTKMIQCAARALGIPSELIHISET 1071

  Fly  1033 DTINGANSMVTGGAVGSETLCFAVRKACETLNERLKPVREEVKPENWQDLIQEAYNRKINLIASD 1097
            .|....|:..|..:|||:....||..|||.||:||.|::|.:....|::.|.:||..:::|.|:.
  Fly  1072 ATDKVPNTSPTAASVGSDLNGMAVLDACEKLNKRLAPIKEALPGGTWKEWINKAYFDRVSLSATG 1136

  Fly  1098 -QCKQG-----DMDP------YSVCGLCLTEVELDVLTGNYIVGRVDILEDTGESLNPNVDIGQI 1150
             ....|     :.:|      |...|:.:|.||:|.|||::.|...||:.|.|.||||.:|||||
  Fly  1137 FYAMPGIGYHPETNPNARTYSYYTNGVGVTVVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQI 1201

  Fly  1151 EGAFMMGLGYWTSEQVIADPKTGECLTNRTWTYKPPGAKDIPTDLRIELLPKSPNKAGFMRSKAT 1215
            |||||.|.|.:|.|:::..|: |...:.....||.||..|||.:..:.||..:||......|||.
  Fly  1202 EGAFMQGYGLFTLEELMYSPQ-GMLYSRGPGMYKLPGFADIPGEFNVSLLTGAPNPRAVYSSKAV 1265

  Fly  1216 GEPAICLSIAVAFALQQALQSARDDAGVPKSWVTLTAPMT 1255
            |||.:.:..:..||:::|:.:||:|.|:...: .|.||.|
  Fly  1266 GEPPLFIGSSAFFAIKEAIAAAREDQGLSGDF-PLEAPST 1304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX1	NP_650475.1	PLN02906	28..1259	CDD:215491	428/1334 (32%)
ry	NP_524337.1	PLN02906	25..1317	CDD:215491	430/1338 (32%)