Protein Alignment AOX1 and LOC100493336

DIOPT Version :9

• Sequence 1: NP_650475.1
• Gene: AOX1 / 41894
• FlyBaseID: FBgn0267408
• Length: 1273
• Species: Drosophila melanogaster
• Sequence 2: XP_002937755.3
• Gene: LOC100493336 / 100493336
• -ID: -
• Length: 1106
• Species: Xenopus tropicalis
• Alignment Length: 1190
• Identity: 294/1190 - (24%)
• Similarity: 476/1190 - (40%)
• Gaps: 243/1190 - (20%)

  Fly   207 LYPDGSRWSWPVSLGDLFAALQGAVKEKLPYM-LVAGNTAHGVYRRSPDIK-------AFIDVSG 263
            |..|.|.|..|..|.:|.     .:|...|.. ||.|||..|     |.:|       ..|.:|.
 Frog    13 LQGDKSTWVTPSCLNELL-----DLKSVYPMAPLVVGNTLIG-----PQVKLTGSYYPVIISLSR 67

  Fly   264 LAELKGHKLSADNSSLTLGGNLSL----SETMELCRQLENTKG--FEYLSQVWQHLDWIANVPVR 322
            :.||.  .:|.....:|:|...||    |...|:..||...||  |..|      |..::...:|
 Frog    68 VPELS--VMSYTEKGITIGAACSLVMVRSILSEVVSQLPEEKGKMFRVL------LQQLSGQNIR 124

  Fly   323 NAGTLAGN-------------LSIKHAHPEFPSDVFIVLEALDAQVIVQEAVDKQQTVSLASYL- 373
            |..:|.|:             |::.|......|.                  |:::.|:|...|
 Frog   125 NEASLGGSILSGSATWELNPILAVGHCTFNLASK------------------DRRRKVTLRQLLF 171

  Fly   374 -----GSSMEGKIIRGLVLRAYPKERFAFDSYKIMPRAQNAHAYVNAAFLVEFTADAK-VKSARI 432
                 .|....:::..:.:....|..|. .::|.:.|.::|...|.||..|....... :.:..|
 Frog   172 GEPGIASLRPEELLISINIPFTKKWEFV-SAFKQIQRWESAVPAVVAAMSVRLKDGTDLILAMNI 235

  Fly   433 CFGGIHPEFVHATAI-ENLI-RDKNPF-----------ENGLVEKAFGQLSTLLQPDAVLPDASP 484
            .:||.....:.|..: |.|| |..|..           |..|.:..||:::.
 Frog   236 YYGGSESACLFAKWVSEQLIGRRWNEAMLDEACRLFLGEIPLQDSTFGEMAD------------- 287

  Fly   485 VYRRKLACGLFYKFLLKIAAQRKQGLGSRFVTGGSLLKR--------PVSSGQQSFE-------- 533
             :.|.||....:||.|:|..:..:...|........|||        |::..||...
 Frog   288 -HERTLAISFIFKFYLQILQELNKNSNSLHKPIYDTLKRNVMLNGKNPINDLQQRISNGFHLNDE 351

  Fly   534 ----------------TFQEHYPVTKATEKHEGLIQCSGEATYSNDLPTQHNQLWAAFVIAKKVG 582
                            |.|.|...|.|.|:.:           :.|......:|:.:.|.:.:..
 Frog   352 DDDLNYSNGGINGETITHQPHMLHTIAEEEID-----------NEDSQVVEGELFLSLVTSTRHH 405

  Fly   583 AKVTKVDTQPALDLPGVVAYLDAKDIPGPNYVGPKIRDQFFFPKDEELFATGEIKFYGQPVGIIL 647
            ||:..:.::.||.:||||..:.|.|:|..|              |:::||..|:.:.||.|..::
 Frog   406 AKIIAIRSEDALKVPGVVDVITAVDVPRAN--------------DKDVFAEHEVHYMGQVVCAVV 456

  Fly   648 ANSNSLANRAAELVKLTYEGGAEEILPSLKAVLDKVGS----------EAGNNKRLEQPIKSTID 702
            |::...|:..|..||:.|    :::.|.:.::.|.:.:          |.||   :|:..::...
 Frog   457 ADTKKHASLGASRVKIEY----QDLEPVILSIQDAIKNNSYFELTRKIEQGN---IEEAFQNADH 514

  Fly   703 VLQLEEPFDVSSSGQLDMGLQYHYYMEPQTTVVLP--FEGGLQVYAATQWMDLTQDTIANVLNLK 765
            :|:.|:..    .||.|.....|      |..|:|  .|..::|..||......|..:|:.||:.
 Frog   515 ILEGEDYI----GGQDDSSYPLH------TLSVIPRLEENEIEVLIATNDPAPIQAAVASALNIP 569

  Fly   766 SNDV--QVKTRRIGGGYGGKATRCNLAAAAAALAAHKLNRPIRFVQSLE-----SIM----TSLG 819
            |:.|  ..:.:|   ..|.:..:....||..|:||||..:.:..|  ||     ||.    ..||
 Frog   570 SDFVICHGEPQR---DVGAQNYQTASLAAITAVAAHKTGQIVHSV--LEWREEGSISRYQPPFLG 629

  Fly   820 KRWAFHCDYDFFVQKSGKISGIVSRFYEDAGYLANESP--IGHTVLLSKNCYEFSDNYKLDGYLV 882
            |       |....:..|.|..:...:|.:||:..:||.  :..::|.::|.| :..|.:......
 Frog   630 K-------YKVAYKSDGTIIALDVTYYCNAGHRLDESSEVLAVSLLSAQNAY-YIPNTRCCVVAC 686

  Fly   883 CTDSPSNTPCRAPGSVEGIAMMENIIEHIAFETGVDPADVRFANL------------LPAHKMGD 935
            .|:|.:...||..|......:.|..::.:|....:.|..||..||            ..:..:..
 Frog   687 KTNSQAKCFCRGCGFPRACMLAEIWVDAVADRCALPPEKVRQINLHGAVSHVAFKRDFDSSNLIK 751

  Fly   936 MMPRFLESTKYRERKAEAIAHNKENRWHKRGLGLCIMEYQIGYFGQY--PATVAIYHS-DGTVVV 997
            .....::.:.|.||...|...||:..|.|:||.:..:.:..|:....  .|:|.::.| ||.|:|
 Frog   752 CWNECMQKSLYHERHTAAKESNKQCPWRKKGLSIIPVMFPAGFIEDVLNQASVLVHVSVDGWVLV 816

  Fly   998 SHGGIEMGQGMNTKISQVAAHTLGIPMEQVRIEASDTINGANSMVTGGAVGSETLCFAVRKACET 1062
            :..|.|..:..:|.:.|||:..|.||:..:.|..::|...:.:.||..:|.|.....|||:||:.
 Frog   817 TPAGNETQEETHTILMQVASRELRIPISHIYISETNTTVSSTTSVTTSSVTSTVYALAVREACQI 881

  Fly  1063 LNERLKPVREEVKPENWQDLIQEAYNRKINLIAS---------DQC-KQGDMDPYSVCGLCLTEV 1117
            |.:||.|:........|.:.:|||::.:|.|.|:         |.| |:|...|..:.|...:||
 Frog   882 LLQRLHPIIILNPDATWLECVQEAFHLRICLSAAGHYRSTKAMDWCLKEGLESPNFIFGAACSEV 946

  Fly  1118 ELDVLTGNYIVGRVDILEDTGESLNPNVDIGQIEGAFMMGLGYWTSEQVIADPKTG-ECLTNRTW 1181
            |||..|||:...|.||:.|.|.|:|...:..||:.||:..|..:.||    |.|.. :...|...
 Frog   947 ELDCRTGNHKCLRTDIVMDVGSSINRTENTEQIKNAFVQSLDIFISE----DFKYSLQGSLNGAQ 1007

  Fly  1182 TYKPPGAKDIPTDLRIELLPKSPNKAGFMRS-KATGEPAICLSIAVAFALQQALQSARDDAGVPK 1245
            ..||...| .|..|.:.|...||.......| ||..|.::....:|.|||:.|:.|||.|||:|.
 Frog  1008 CEKPEVVK-APEQLNVTLPMSSPLNLNVSCSPKAIEETSLFFGTSVFFALKDAVLSARKDAGLPG 1071

  Fly  1246 SWVTLTAPMTPEHLVLHSGT 1265
            : |:|..|:.|:||.:..|:
 Frog  1072 T-VSLPIPVRPQHLKIACGS 1090

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AOX1	NP_650475.1	fer2	4..85	CDD:238126
		PLN02906	28..1259	CDD:215491	291/1182 (25%)
		Fer2_2	86..159	CDD:280048
		FAD_binding_4	211..373	CDD:303082	43/188 (23%)
		CO_deh_flav_C	399..502	CDD:281449	26/116 (22%)
		Ald_Xan_dh_C	555..666	CDD:214971	27/110 (25%)
		Ald_Xan_dh_C2	711..1192	CDD:280834	141/521 (27%)
LOC100493336	XP_002937755.3	mam_aldehyde_ox	2..1092	CDD:132014	294/1190 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D48717at2759
OrthoFinder	1	1.000	-	-		FOG0000201
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920