DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5213 and PAB1

DIOPT Version :9

Sequence 1:	NP_650473.1	Gene:	CG5213 / 41892	FlyBaseID:	FBgn0038345	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_011092.1	Gene:	PAB1 / 856912	SGDID:	S000000967	Length:	577	Species:	Saccharomyces cerevisiae

Alignment Length:	238	Identity:	60/238 - (25%)
Similarity:	100/238 - (42%)	Gaps:	46/238 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IRGMFQTGRPVDPPPPLPNLRMK----------TNLILNYLPQDMTESELHRLFSKFGEIRKAKI 72
            :.||...|:.:...|.|......          |||.:..:..:.|:.:...||:|||.|..|.:
Yeast   186 LNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASL 250

  Fly    73 IRHRRTGISCCYGFVDYVSERQAAAAVNGMDGYETRGKRLKVAFAR---------PSEYES---- 124
            .:. ..|....:|||:|.....|..||..::..|..|::|.|..|:         ..:||:
Yeast   251 EKD-ADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLE 314

  Fly   125 -----TSSSLYVGNLPTYMDEKKVRELFATYGNIVDVNLLRHKFNNRSRGVAFLQFELVRDAEVA 184
                 ...:|:|.||...:|::|:.|.||.||.|....::|.: |.:|:|..|:.|....:|..|
Yeast   315 KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTE-NGKSKGFGFVCFSTPEEATKA 378

  Fly   185 KYGMDRYMIEGASRPLTVKFVEREKKGSSSTSSGSQYKDKRKS 227
            ....::.::.|  :||.|...:|              ||.|:|
Yeast   379 ITEKNQQIVAG--KPLYVAIAQR--------------KDVRRS 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821	23/75 (31%)
CG5213	NP_650473.1	RRM	128..202	CDD:214636	23/73 (32%)
PAB1	NP_011092.1	PABP-1234	38..559	CDD:130689	60/238 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910