Protein Alignment CG5213 and SRSF1

DIOPT Version :9

• Sequence 1: NP_650473.1
• Gene: CG5213 / 41892
• FlyBaseID: FBgn0038345
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_008855.1
• Gene: SRSF1 / 6426
• HGNCID: 10780
• Length: 248
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 55/243 - (22%)
• Similarity: 87/243 - (35%)
• Gaps: 60/243 - (24%)

  Fly    48 LPQDMTESELHRLFSKFGEIRKAKIIRHRRTGISCCYGFVDYVSERQAAAAVNGMDGYETRGKRL 112
            ||.|:...::..:|.|:|.||... :::||.|..  :.||::...|.|..||.|.|||:..|.||
Human    23 LPPDIRTKDIEDVFYKYGAIRDID-LKNRRGGPP--FAFVEFEDPRDAEDAVYGRDGYDYDGYRL 84

  Fly   113 KVAFAR------------------------PSEYESTSSSLYVGNLPTYMDEKKVRELFATYGNI 153
            :|.|.|                        ||  ..:.:.:.|..||.....:.:::.....|::
Human    85 RVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPS--RRSENRVVVSGLPPSGSWQDLKDHMREAGDV 147

  Fly   154 VDVNLLRHKFNNRSRGVAFLQFELVRDAEVAKYGMD--------------RYMIEGASRP----L 200
            ...::.|.       |...::|....|...|...:|              |..::|...|    .
Human   148 CYADVYRD-------GTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRS 205

  Fly   201 TVKFVEREKKGSSSTSSGSQYKDKRKSSPPPYKRRERTNDHHVSKRSR 248
            ..:...|.:..|.|.|....|..:|....|.|..|      |...|||
Human   206 RSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPR------HSRSRSR 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821	25/68 (37%)
		RRM	128..202	CDD:214636	13/91 (14%)
SRSF1	NP_008855.1	RRM1_SRSF1	12..90	CDD:410010	26/69 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..134		7/47 (15%)
		RRM2_SRSF1	113..196	CDD:410160	13/91 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	191..248		16/63 (25%)
		Interaction with SAFB1	198..247		12/54 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010