DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5213 and hnrnpa1

DIOPT Version :9

Sequence 1:	NP_650473.1	Gene:	CG5213 / 41892	FlyBaseID:	FBgn0038345	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_012812298.1	Gene:	hnrnpa1 / 496507	XenbaseID:	XB-GENE-493963	Length:	362	Species:	Xenopus tropicalis

Alignment Length:	162	Identity:	42/162 - (25%)
Similarity:	74/162 - (45%)	Gaps:	14/162 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 MFQTGRPVDPPPPLPNLRMKTNLILNYLPQDMTESELHRLFSKFGEIRKAKIIRHRRTGISCCYG 85
            |.::..|.:|    ..||   .|.:..|..:.|:..|...|.::|.:....::|...:..|..:|
Frog     1 MHKSEAPKEP----EQLR---KLFIGGLSFETTDESLREHFEQWGTLTDCVVMRDPNSKRSRGFG 58

  Fly    86 FVDYVSERQAAAAVNG----MDGYETRGKRL--KVAFARPSEYESTSSSLYVGNLPTYMDEKKVR 144
            ||.|.|..:..||::.    :||.....||.  :...:||..: .|...::||.:....:|..:|
Frog    59 FVTYSSTDEVDAAMSARPHKVDGRVVEPKRAVSREDSSRPGAH-LTVKKIFVGGIKEDTEEHHLR 122

  Fly   145 ELFATYGNIVDVNLLRHKFNNRSRGVAFLQFE 176
            |.|..||.|..:.::..:.:.:.||.||:.||
Frog   123 EYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFE 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821	19/81 (23%)
CG5213	NP_650473.1	RRM	128..202	CDD:214636	15/49 (31%)
hnrnpa1	XP_012812298.1	RRM1_hnRNPA1	12..92	CDD:241205	21/82 (26%)
		RRM2_hnRNPA1	105..181	CDD:241024	15/50 (30%)
		HnRNPA1	<315..>334	CDD:371635
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920