DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5213 and HNRNPAB

DIOPT Version :9

Sequence 1:	NP_650473.1	Gene:	CG5213 / 41892	FlyBaseID:	FBgn0038345	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_112556.2	Gene:	HNRNPAB / 3182	HGNCID:	5034	Length:	332	Species:	Homo sapiens

Alignment Length:	190	Identity:	48/190 - (25%)
Similarity:	87/190 - (45%)	Gaps:	21/190 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LPQDMTESELHRLFSKFGEIRKAKIIRHRRTGISCCYGFVDYVSERQAAAAVNGMDGYETR--GK 110
            |..|.::.:|...|:||||:....|.....||.|..:||:.:   :.||:....:|..|.|  |:
Human    77 LSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILF---KDAASVEKVLDQKEHRLDGR 138

  Fly   111 RL--KVAFARPSEYESTSSSLYVGNLPTYMDEKKVRELFATYGNIVDVNLLRHKFNNRSRGVAFL 173
            .:  |.|.|...:   ....::||.|.....|:|:||.|..:|.|..:.|......|:.||..|:
Human   139 VIDPKKAMAMKKD---PVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFI 200

  Fly   174 QFELVRDAEVAKYGMDR--YMIEGASRPLTV----KFVEREKKGSSSTSSGSQYKDKRKS 227
            .|   ::.|..|..:::  :.:.|:...:.|    :..::::.||.  ..|::.:..|.|
Human   201 TF---KEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSG--GRGNRNRGNRGS 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821	22/72 (31%)
CG5213	NP_650473.1	RRM	128..202	CDD:214636	19/75 (25%)
HNRNPAB	NP_112556.2	CBFNT	1..70	CDD:311868
		RRM1_hnRNPAB	66..145	CDD:410151	21/70 (30%)
		RRM2_hnRNPAB	150..229	CDD:409997	19/84 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920