DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5213 and TRA2A

DIOPT Version :9

Sequence 1:	NP_650473.1	Gene:	CG5213 / 41892	FlyBaseID:	FBgn0038345	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_037425.1	Gene:	TRA2A / 29896	HGNCID:	16645	Length:	282	Species:	Homo sapiens

Alignment Length:	163	Identity:	39/163 - (23%)
Similarity:	63/163 - (38%)	Gaps:	45/163 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 SSSLYVGNLPTYMDEKKVRELFATYGNIVDVNLLRHKFNNRSRGVAFLQFELVRDAEVA------ 184
            ::.|.|..|..|..|:.:||:|:.||.:..||::..:...||||.||:.||.:.|::.|
Human   118 NTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANG 182

  Fly   185 ------KYGMDRYMIEGASRPLTVKFVEREKKGSSSTSSG------------------------S 219
                  :..:|..:.:.|..|....::.|..........|                        .
Human   183 MELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYD 247

  Fly   220 QYKD----KRKSSPPPYKRRERTNDHHVSKRSR 248
            :|:|    .|:.||.||..|.|:.     .|||
Human   248 RYEDYDYRYRRRSPSPYYSRYRSR-----SRSR 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821
CG5213	NP_650473.1	RRM	128..202	CDD:214636	25/85 (29%)
TRA2A	NP_037425.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..118		39/163 (24%)
		RRM_TRA2	118..197	CDD:409798	23/78 (29%)
		Linker	198..225		4/26 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..245		3/43 (7%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	260..282		9/21 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_117020
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810