DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5213 and HNRNPA3

DIOPT Version :9

Sequence 1:	NP_650473.1	Gene:	CG5213 / 41892	FlyBaseID:	FBgn0038345	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001317178.1	Gene:	HNRNPA3 / 220988	HGNCID:	24941	Length:	378	Species:	Homo sapiens

Alignment Length:	203	Identity:	55/203 - (27%)
Similarity:	89/203 - (43%)	Gaps:	27/203 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DPPPPLPNLRMKTNLILNYLPQDMTESELHRLFSKFGEIRKAKIIRHRRTGISCCYGFVDY--VS 91
            ||..| ..||   .|.:..|..:.|:..|...|.|:|.:....::|..:|..|..:|||.|  |.
Human    27 DPKEP-EQLR---KLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVE 87

  Fly    92 ERQAA--AAVNGMDGYETRGKRLKVAFARPSEYES----TSSSLYVGNLPTYMDEKKVRELFATY 150
            |..||  |..:.:||.....||   |.:|....:.    |...::||.:....:|..:|:.|..|
Human    88 EVDAAMCARPHKVDGRVVEPKR---AVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKY 149

  Fly   151 GNIVDVNLLRHKFNNRSRGVAFLQF---ELVRDAEVAKYGMDRYMIEGASRPLTVKFVEREKKGS 212
            |.|..:.::..:.:.:.||.||:.|   :.|....|.||    :.|.|.:..:.....::|.:
Human   150 GKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKY----HTINGHNCEVKKALSKQEMQ-- 208

  Fly   213 SSTSSGSQ 220
               |:|||
Human   209 ---SAGSQ 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821	24/79 (30%)
CG5213	NP_650473.1	RRM	128..202	CDD:214636	19/76 (25%)
HNRNPA3	NP_001317178.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35		3/8 (38%)
		RRM1_hnRNPA_like	36..113	CDD:409992	24/79 (30%)
		RRM2_hnRNPA3	126..205	CDD:409996	19/82 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..225		5/15 (33%)
		HnRNPA1	331..>347	CDD:402981
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	336..378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920