DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5213 and HNRNPA0

DIOPT Version :9

Sequence 1:	NP_650473.1	Gene:	CG5213 / 41892	FlyBaseID:	FBgn0038345	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_006796.1	Gene:	HNRNPA0 / 10949	HGNCID:	5030	Length:	305	Species:	Homo sapiens

Alignment Length:	187	Identity:	50/187 - (26%)
Similarity:	82/187 - (43%)	Gaps:	15/187 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LILNYLPQDMTESELHRLFSKFGEIRKAKIIRHRRTGISCCYGFVDYVSERQA----AAAVNGMD 103
            |.:..|....:||.|...|..||.:....::.:.:|..|.|:|||.|.:..:|    ||:.:.:|
Human     9 LFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVD 73

  Fly   104 GYETRGKRL--KVAFARPSEYESTSSSLYVGNLPTYMDEKKVRELFATYGNIVDVNLLRHKFNNR 166
            |.....||.  :...|||..:... ..|:||.|...:.|..:.|.|:.:|.:....::..|.:.:
Human    74 GNTVELKRAVSREDSARPGAHAKV-KKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGK 137

  Fly   167 SRGVAFLQF---ELVRDAEVAKYGMDRYMIEGASRPLTVKFVEREKKGSSSTSSGSQ 220
            .||..|:.|   :....|.|.|:    :.|:| .|....|.|.:|...|.....||:
Human   138 KRGFGFVYFQNHDAADKAAVVKF----HPIQG-HRVEVKKAVPKEDIYSGGGGGGSR 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5213	NP_650473.1	RRM1_Hu_like	41..117	CDD:240821	22/79 (28%)
CG5213	NP_650473.1	RRM	128..202	CDD:214636	19/76 (25%)
HNRNPA0	NP_006796.1	RRM1_hnRNPA0	5..83	CDD:240772	22/73 (30%)
		RRM2_hnRNPA0	99..178	CDD:241023	21/83 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..214		5/16 (31%)
		HnRNPA1	255..>269	CDD:314495
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..305
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010