Protein Alignment obe and mus301

DIOPT Version :10

• Sequence 1: NP_650472.2
• Gene: obe / 41891
• FlyBaseID: FBgn0038344
• Length: 2183
• Species: Drosophila melanogaster
• Sequence 2: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Alignment Length: 974
• Identity: 207/974 - (21%)
• Similarity: 377/974 - (38%)
• Gaps: 244/974 - (25%)

  Fly  1259 QSQQLVM-TIPLKEPLPPQYYIRVSSDNWLG---------------STTCIPLSFQHLVLP---- 1303
            |:.||.: .:..|:|..|:..:....|:.:.               ..||..|..|.|:.|
  Fly   157 QNTQLFLDAMTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWE 221

  Fly  1304 --------------EHHPPLTEL--LPLRPLPVSCLKNVVYE-----SLYKFTHFNPIQTQIFHC 1347
                          :..|...|.  ||.:      :|.::.|     |||::..         .|
  Fly   222 TQAFADFEKNNQDIDKFPSKGEFYGLPDK------VKKMILEHKGINSLYEWQD---------EC 271

  Fly  1348 L----YHTDNNVLLGAPTGSGKTIVAEIAIFRALNQNPKCK---VVYIAPLKALVKERIADWEQR 1405
            |    .....|::...||..|||:||||.:.|.|    .|:   |::|.|..::|:|::
  Fly   272 LNLPAIRQRKNLIYALPTSGGKTLVAEILMLREL----LCRERNVLFILPYVSIVQEKV------ 326

  Fly  1406 FQRSSLGLKVVEL----------TGDVTPDIQAIRESQLIVTTPEKWDGISRSWQTREYVQHVSL 1460
               |::....::|          .|...|..:..|.| |.:.:.||...:..|....:....:.|
  Fly   327 ---SAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRS-LFIASIEKGAVLMDSLIDVQRPHEIGL 387

  Fly  1461 IVIDEIHLLGE-DRGPVIEVIVSRTNFISSHTGRAIRIVGLSTALANAQDLANWLGINKMGLYNF 1524
            :|:||:||:|| .||..:|..:::..|::::    |:|||:|..:.|..:::::|..:.     :
  Fly   388 VVVDELHLIGEKGRGATLEAFLTKVMFLNAN----IQIVGMSATIGNLSEISSFLNADV-----Y 443

  Fly  1525 KPSVRPVPLQVHINGFPG------------KHYCP-RMATMNRPTFQAIRTYSP---------CE 1567
            ....|||.|:.:|...|.            :.:.| |....|..  :|::...|         |.
  Fly   444 TRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYS--EAVKRADPDHLAGLISECA 506

  Fly  1568 P---TIVFVSSRRQTRLTALDLITFVAGESNPKQ--FLHIPEDEIELI-----LQNIREQNLKFC 1622
            |   .:||..||:.....||.|...|     ||.  |.|...::::|:     :..|....|...
  Fly   507 PEHCCLVFCPSRKNCENVALLLSRIV-----PKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKT 566

  Fly  1623 LAFGIGLHHAGLQEQDRKCVEELFLNRKIQILVATATLAWGVNLPAHLVVIK----GTEYFDGKV 1683
            |.:||..||:||...:||.:|..:....:.::..|:|||.||||||..|:|:    |.|:
  Fly   567 LPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEF----- 626

  Fly  1684 KKYVDMPITDVLQMMGRAGRPQFDNEGVAVVLVHDEKKNFYKKFLYDPFP-------------VE 1735
                 :.:....||:|||||......|.::::...:......:.|:.|..             ::
  Fly   627 -----LTLCKYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQ 686

  Fly  1736 SSLLGV-----------LPEHINAEIVAGTVQSKQAALDYLTWTYFFRRLLRNPSYYQLQDIEPE 1789
            |.:|.|           |...:|:.:::...:|.:.|::.:. ....|.:.:|.   .||..||:
  Fly   687 SLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIV-LRILREMFKNK---VLQLAEPQ 747

  Fly  1790 NVNNFMSN--LVERVVYELSAAA----CLVERDGCLIPTFLGRISSYYYLSYRTMKHFLEDLQPG 1848
            ..:...|:  :..:.|.:.:..|    .|:.:......|.:||.:....:.|:......::|:..
  Fly   748 AKSKINSSDIITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQA 812

  Fly  1849 MNTKKVLLAIADSYEFDQLPVRHNEDKHNEEMAEVSRFRPPSSSWDSSYTKTFLLLQAHFARQSL 1913
            ...    |.:.:......|.|..|.::..:|:     |...:|.....||...|..||.|.:...
  Fly   813 QQQ----LILTNYLHLLYLVVCFNSNERGDEL-----FPADASILFGVYTSLPLDSQAMFKQLGF 868

  Fly  1914 PNSDYLTDTKSALDNATRVMQAMVDYTAERGWLSTTLVVQQLMQSVIQARWFDGSEFLTLPGVNE 1978
            ..:           :|.|:.:..    :.:|.||  |.:.:|.:.:|.|   |....|.:|.|..
  Fly   869 TEA-----------HAARLFKTQ----SVQGPLS--LQLNRLYKVLILA---DILNLLPIPSVAS 913

  Fly  1979 DNLDAFLNIPHDDYDYL------TLPVLKELCKQEYEVLA-KPLRDAFEE--HEIEKM----YKV 2030
            .     .|:......:|      ....:..||::..|... |||   ||.  |::::.    .:.
  Fly   914 K-----YNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPL---FERILHKMDRCGTFELEP 970

  Fly  2031 IQDLPEIAI----QIFVEGRHMENEYAK-RPLSLSDDTRGEWMSLHANEDYV---LIVNLQRLN 2086
            :.:||.:.|    |::..|.....:.|: ||..|....  |.|.|....:.|   .|:.:::|:
  Fly   971 LMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSL--EHMPLRVATEIVSAAKIILMKKLD 1032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
obe	NP_650472.2	Helicase_PWI	<247..>284	CDD:436309
		BRR2	485..1025	CDD:440817
		DEXHc_ASCC3_1	486..683	CDD:350778
		SEC63	985..1298	CDD:214744	10/54 (19%)
		BRR2	1334..1859	CDD:440817	134/608 (22%)
		DEXHc_ASCC3_2	1336..1525	CDD:350780	49/206 (24%)
		SEC63	1818..2176	CDD:214744	57/290 (20%)
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	56/239 (23%)
		BRR2	255..828	CDD:440817	138/629 (22%)