DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rh6 and RGR

DIOPT Version :9

Sequence 1:NP_524368.5 Gene:Rh6 / 41889 FlyBaseID:FBgn0019940 Length:369 Species:Drosophila melanogaster
Sequence 2:NP_002912.2 Gene:RGR / 5995 HGNCID:9990 Length:295 Species:Homo sapiens


Alignment Length:315 Identity:81/315 - (25%)
Similarity:122/315 - (38%) Gaps:49/315 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 PMWFG-----IIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFPP 103
            |..||     .:|.|:.:.....|:.|.:.::.|..:..||||.::.|::||.:|..:.......
Human     8 PTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVA 72

  Fly   104 V---VLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIA---YDRYCVIVKGMARKPLTATA 162
            .   :|...:..|..|...|:.:|..|.:....||.|...||   |..||      .|..|...:
Human    73 ATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC------TRSQLAWNS 131

  Fly   163 AVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWVYLTPLLTI 227
            ||..::.||.....||.:||.||..|..|...|.|..||...|....|::...|.:.:..||...
Human   132 AVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFIT 196

  Fly   228 IFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTI 292
            |.||                        ||...:..||..:::.....|.|.:    ..|.||.|
Human   197 ITSY------------------------SLMEQKLGKSGHLQVNTTLPARTLL----LGWGPYAI 233

  Fly   293 IN-YAGIFESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLA 346
            :. ||.|.:...:||...:..::.||.....|.|.|.|.:   :.|.|....||:
Human   234 LYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGN---EMVCRGIWQCLS 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rh6NP_524368.5 7tmA_photoreceptors_insect 48..338 CDD:320207 75/301 (25%)
TM helix 1 50..74 CDD:320207 5/23 (22%)
TM helix 2 83..105 CDD:320207 4/24 (17%)
TM helix 3 121..143 CDD:320207 7/24 (29%)
TM helix 4 165..181 CDD:320207 4/15 (27%)
TM helix 5 209..232 CDD:320207 6/22 (27%)
TM helix 6 273..295 CDD:320207 6/22 (27%)
TM helix 7 306..331 CDD:320207 7/24 (29%)
RGRNP_002912.2 7tmA_Retinal_GPR 17..281 CDD:320200 76/300 (25%)
TM helix 1 18..44 CDD:320200 5/25 (20%)
TM helix 2 51..77 CDD:320200 4/25 (16%)
TM helix 3 92..122 CDD:320200 9/29 (31%)
TM helix 4 130..150 CDD:320200 6/19 (32%)
TM helix 5 177..206 CDD:320200 9/52 (17%)
TM helix 6 208..238 CDD:320200 8/33 (24%)
TM helix 7 248..273 CDD:320200 7/24 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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