DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and rhol

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001103501.1	Gene:	rhol / 562845	ZFINID:	ZDB-GENE-070424-6	Length:	355	Species:	Danio rerio

Alignment Length:	348	Identity:	91/348 - (26%)
Similarity:	167/348 - (47%)	Gaps:	30/348 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PYWY-QWPPLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMM 97
            ||.| |:....|..|..:...:..|....:..|.:.:|:...:|.||||.|..::|||.:|..|:
Zfish    23 PYEYPQYYLASPFAFYCMAAYMLFLIVTCVPVNGLTLYVTIENKKLRTPLNYILLNLAVADLFMV 87

  Fly    98 FTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATA 162
            |..|........:|.:::|...|.|.|:|.::.|.:::||:.::|.:|:.|:.|...:...:...
Zfish    88 FGGFTTTFYTSMHGYFVLGRAGCNLEGLFATVGGEIALWSLVVLAVERWVVVCKPFTKFRFSQLH 152

  Fly   163 AVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFA--KDWWNRSYIIVYSLWVYLTPLL 225
            |.|.:...|::..:.|:.||.||:||:|||...:||.||:.  .:..|.|::|...:..:..||.
Zfish   153 ATLGVAFSWSMACSCAIPPLLGWSRYIPEGLQCSCGVDYYTPNPETENESFVIYMFVVHFSIPLT 217

  Fly   226 TIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPY 290
            .|.|.|..::..|              .||:.:..|::.::..|.::.::.:..:..:...|.||
Zfish   218 IISFCYGRLLCTV--------------KVAAAQQQESETTQRAEREVTRMVILMVIAFLICWLPY 268

  Fly   291 -TIINYAGIFESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGKDDL-- 352
             ::..|....:.....|:.....:.|||::|:.||::|...:   ||.....|..:.||||..
Zfish   269 ASVAWYIFTHQGSQFGPVFMTVPAFFAKSSALYNPLIYVFMN---KQFRHSMMMTVCCGKDPFQD 330

  Fly   353 ------TSDSRTQATAEISESQA 369
                  :|.|:|: |:.:|.|.|
Zfish   331 EEEGSSSSKSKTE-TSSVSSSSA 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	73/292 (25%)
		TM helix 1	50..74	CDD:320207	3/23 (13%)
		TM helix 2	83..105	CDD:320207	8/21 (38%)
		TM helix 3	121..143	CDD:320207	6/21 (29%)
		TM helix 4	165..181	CDD:320207	3/15 (20%)
		TM helix 5	209..232	CDD:320207	6/22 (27%)
		TM helix 6	273..295	CDD:320207	3/22 (14%)
		TM helix 7	306..331	CDD:320207	8/24 (33%)
rhol	NP_001103501.1	Rhodopsin_N	2..37	CDD:287397	5/13 (38%)
rhol	NP_001103501.1	7tm_1	55..306	CDD:278431	69/264 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48050
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920