DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and opn3

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001104634.1	Gene:	opn3 / 561815	ZFINID:	ZDB-GENE-080227-16	Length:	387	Species:	Danio rerio

Alignment Length:	313	Identity:	87/313 - (27%)
Similarity:	154/313 - (49%)	Gaps:	20/313 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 FGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFPPVVLNGFYG 111
            :.::.|.|..:|.:....|.||:.:::..|.||||:|:.:||::.||.::..|......::....
Zfish    25 YKLLTFTIGSIGVLGFCNNIIVIILYSRYKRLRTPTNLLIVNISVSDLLVSLTGVNFTFVSCVKR 89

  Fly   112 TWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAVLRLMVVWTICGA 176
            .|:.....|...|...||||.|||.:::.:||:||..:|..   |.:....|...:..:|....|
Zfish    90 RWVFNSATCVWDGFSNSLFGIVSIMTLSGLAYERYIRVVHA---KVVDFPWAWRAITHIWLYSLA 151

  Fly   177 WALMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWVYLTPLLTIIFSYWHIMKAVAAH 241
            |...||.|||||..|.:...|..|:.:||..:.|:|:.:.|..:..|:..:::.|.:|:..|
Zfish   152 WTGAPLLGWNRYTLEVHQLGCSLDWASKDPNDASFILFFLLGCFFVPVGVMVYCYGNILYTV--- 213

  Fly   242 EKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTIINYAGIF-ESMHLS 305
             |.:|      ::..|:..:..|....|.|:|.:.|..||.:...||||.:::....| :...:|
Zfish   214 -KMLR------SIQDLQTVQTIKILRYEKKVAVMFLMMISCFLVCWTPYAVVSMLEAFGKKSVVS 271

  Fly   306 PLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGKDDLTSDSRT 358
            |...|..|:|||::...||::|.....|:::.:.:    :.|.:  |||...|
Zfish   272 PTVAIIPSLFAKSSTAYNPVIYAFMSRKFRRCMLQ----MLCSR--LTSLQHT 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	82/290 (28%)
		TM helix 1	50..74	CDD:320207	6/23 (26%)
		TM helix 2	83..105	CDD:320207	6/21 (29%)
		TM helix 3	121..143	CDD:320207	8/21 (38%)
		TM helix 4	165..181	CDD:320207	3/15 (20%)
		TM helix 5	209..232	CDD:320207	4/22 (18%)
		TM helix 6	273..295	CDD:320207	8/21 (38%)
		TM helix 7	306..331	CDD:320207	9/24 (38%)
opn3	NP_001104634.1	7tm_1	43..293	CDD:278431	77/262 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910