DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rh6 and valopb

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001103750.1	Gene:	valopb / 560921	ZFINID:	ZDB-GENE-040724-41	Length:	392	Species:	Danio rerio

Alignment Length:	328	Identity:	84/328 - (25%)
Similarity:	158/328 - (48%)	Gaps:	31/328 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SLAESVPAEIMHMVDPYWYQWPPLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSN 83
            |:.||  .::....||:......:.|..:..:..::.|:.::|:..||.||.:....|.||.|.|
Zfish     7 SVTES--TDVTTPDDPFKGPLKSVAPWNYTFLACLMFIVTSLSITENFTVMLVTYRFKQLRKPLN 69

  Fly    84 MFVVNLAFSDFMMMFTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCV 148
            ..:|||:.:||::..|......|....|.:.:|.:.|.|.|...:.||.|::||:.::|::|:.|
Zfish    70 YIIVNLSVADFLVSMTGGTISFLTNARGFFFLGVWACVLEGFAVTFFGIVALWSLAILAFERFFV 134

  Fly   149 IVKGMARKPLTATAAVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYII 213
            |.:.:....|....|.:.|:.|||....|.:.|:.|||.|......|.|..::::.::::.:|||
Zfish   135 ICRPLKNVRLGGKHAAMGLIFVWTFSFIWTIPPVLGWNSYTVSKIGTTCEPNWYSTNYYDHTYII 199

  Fly   214 VYSLWVYLTPLLTIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALT 278
            .:.:..::.||..||.||..:|              :|:...|..:.....::..:.::|::.:.
Zfish   200 TFFVTCFILPLGVIIISYGKLM--------------QKLRKVSNTHGRLGNARKPDREVARMVVV 250

  Fly   279 TISLWFFAWTPYTIINYAGIFESMHLSPLSTI-----CGSV---FAKANAVCNPIVYGLSHPKYK 335
            .|..:...||||...       |:.::...||     .||:   |:|..||.|||:|...:.:::
Zfish   251 MIVAFMVGWTPYAAF-------SITVTACPTIYIDPRLGSIPAFFSKTAAVYNPIIYVFMNKQFR 308

  Fly   336 QVL 338
            :.|
Zfish   309 KCL 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	77/297 (26%)
		TM helix 1	50..74	CDD:320207	6/23 (26%)
		TM helix 2	83..105	CDD:320207	7/21 (33%)
		TM helix 3	121..143	CDD:320207	7/21 (33%)
		TM helix 4	165..181	CDD:320207	5/15 (33%)
		TM helix 5	209..232	CDD:320207	8/22 (36%)
		TM helix 6	273..295	CDD:320207	6/21 (29%)
		TM helix 7	306..331	CDD:320207	12/32 (38%)
valopb	NP_001103750.1	7tm_4	38..315	CDD:304433	78/295 (26%)
valopb	NP_001103750.1	7tm_1	50..300	CDD:278431	74/270 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910