DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and opn1lw2

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001002443.1	Gene:	opn1lw2 / 436716	ZFINID:	ZDB-GENE-040718-141	Length:	356	Species:	Danio rerio

Alignment Length:	334	Identity:	85/334 - (25%)
Similarity:	154/334 - (46%)	Gaps:	37/334 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LEPMWFGIIG----FVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFP 102
            :.|.|...:.    |.:.:..|.:   |.:|:......|.||.|.|..:||||.:|  :..|:|.
Zfish    43 IAPRWVYNVATVWMFFVVVASTFT---NGLVLVATAKFKKLRHPLNWILVNLAIAD--LGETLFS 102

  Fly   103 PV--VLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAVL 165
            ..  |:|..:|.:|:|..:|...|...|:.|...:||:|:|:::|:.|:.|...........|..
Zfish   103 STISVINQVFGYFILGHPMCIFEGYTVSVCGIAGLWSLTVISWERWVVVCKPFGNVKFDGKWASA 167

  Fly   166 RLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFA--KDWWNRSYIIVYSLWVYLTPLLTII 228
            .::..|.....|...|:|||:||.|.|..|:||.|.|.  :|...:||::|..:...:.||..||
Zfish   168 GIIFSWVWAAVWCAPPIFGWSRYWPHGLKTSCGPDVFGGNEDPGVQSYMLVLMITCCILPLAIII 232

  Fly   229 FSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTII 293
            ..|..:..|:    .|:.:|.|          :::.::..|.:::::.:..:..:...|.|||..
Zfish   233 LCYIAVFLAI----HAVAQQQK----------DSESTQKAEKEVSRMVVVMVLAFCLCWGPYTAF 283

  Fly   294 N-YAGIFESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGK--DD--LT 353
            . :|.........||:....:.|||:..:.|||:|...:.:::..:.:..     ||  ||  ..
Zfish   284 ACFAAANPGYAFHPLAAAMPAYFAKSATIYNPIIYVFMNRQFRVCIMQLF-----GKKVDDGSEV 343

  Fly   354 SDSRTQATA 362
            |.|:|:.::
Zfish   344 STSKTEVSS 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	76/298 (26%)
		TM helix 1	50..74	CDD:320207	4/27 (15%)
		TM helix 2	83..105	CDD:320207	8/23 (35%)
		TM helix 3	121..143	CDD:320207	7/21 (33%)
		TM helix 4	165..181	CDD:320207	2/15 (13%)
		TM helix 5	209..232	CDD:320207	7/22 (32%)
		TM helix 6	273..295	CDD:320207	4/22 (18%)
		TM helix 7	306..331	CDD:320207	9/24 (38%)
opn1lw2	NP_001002443.1	7tm_4	57..>185	CDD:304433	36/132 (27%)
opn1lw2	NP_001002443.1	7tm_1	67..318	CDD:278431	73/266 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910