DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and opn1mw3

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_878312.1	Gene:	opn1mw3 / 360152	ZFINID:	ZDB-GENE-030728-6	Length:	349	Species:	Danio rerio

Alignment Length:	367	Identity:	95/367 - (25%)
Similarity:	177/367 - (48%)	Gaps:	40/367 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 DGRNLSLAESVPAEIMHMVDPYWY-QWPPLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKG 77
            :|.|..:..|....::.  .||.| |:...||..|.::...:..|.......|.:.:.:....|.
Zfish     5 EGNNFYIPMSNRTGLVR--SPYEYPQYYLAEPWQFKLLAVYMFFLMCFGFPINGLTLVVTAQHKK 67

  Fly    78 LRTPSNMFVVNLAFSDFMMM---FTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMT 139
            ||.|.|..:||||.:..:|:   ||:.....:||::   ::||..|.:.|...:|.|.:|:||:.
Zfish    68 LRQPLNFILVNLAVAGTIMVCFGFTVTFYTAINGYF---VLGPTGCAIEGFMATLGGQISLWSLV 129

  Fly   140 LIAYDRYCVIVKGMARKPLTATAAVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFA- 203
            ::|.:||.|:.|.|.....::..|...:...|.:..:.|..||.||:||:|||...:||.||:.
Zfish   130 VLAIERYIVVCKPMGSFKFSSNHAFAGIGFTWIMALSCAAPPLVGWSRYIPEGMQCSCGPDYYTL 194

  Fly   204 -KDWWNRSYIIVYSLWVYLTPLLTIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKA 267
             .|:.|.||::......::.|:.||.|:|..::..|.|              |:.:..|::.::.
Zfish   195 NPDYNNESYVLYMFCCHFIFPVTTIFFTYGRLVCTVKA--------------AAAQQQESESTQK 245

  Fly   268 IEIKLAKVALTTISLWFFAWTPYTII------NYAGIFESMHLSPLSTICGSVFAKANAVCNPIV 326
            .|.::.::.:..:..:..|||||..:      |....|.:..::     ..:.|:|::::.|||:
Zfish   246 AEREVTRMVILMVLGFLVAWTPYASVAAWIFFNRGAAFSAQFMA-----VPAFFSKSSSIFNPII 305

  Fly   327 YGLSHPKYKQVLREKMPCLACGKDDLTSD-SRTQATAEISES 367
            |.|.:.:::..:   :..|.|||:.|..| |.|.:|::...|
Zfish   306 YVLLNKQFRNCM---LTTLFCGKNPLGDDESSTVSTSKTEVS 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	75/300 (25%)
		TM helix 1	50..74	CDD:320207	2/23 (9%)
		TM helix 2	83..105	CDD:320207	8/24 (33%)
		TM helix 3	121..143	CDD:320207	6/21 (29%)
		TM helix 4	165..181	CDD:320207	2/15 (13%)
		TM helix 5	209..232	CDD:320207	6/22 (27%)
		TM helix 6	273..295	CDD:320207	5/27 (19%)
		TM helix 7	306..331	CDD:320207	7/24 (29%)
opn1mw3	NP_878312.1	Rhodopsin_N	2..37	CDD:287397	9/33 (27%)
		7tm_4	45..>248	CDD:304433	60/219 (27%)
		7tm_1	55..306	CDD:278431	72/272 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	329..349		5/16 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48050
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920