DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and Rgr

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_038950404.1	Gene:	Rgr / 306307	RGDID:	1309174	Length:	300	Species:	Rattus norvegicus

Alignment Length:	341	Identity:	81/341 - (23%)
Similarity:	128/341 - (37%)	Gaps:	73/341 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 PMWFG-----IIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSD---------- 93
            |..||     .||.|:.:.....::.|.:.::.|..:..||||||:.|::||.:|
  Rat     8 PAGFGELEVLAIGIVLLMEALSGISLNGLTIFSFCKTPDLRTPSNLLVLSLALADTGISLNALVA 72

  Fly    94 -FMMMFTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIA---YDRYCVIVKGMA 154
             ...:..:..|:|   .:..|..|...|.::|..|......||.....||   |..||      .
  Rat    73 AVSSLLRVILPIV---SHRRWPHGSEGCRVHGFQGFATALASICGSAAIAWGRYHHYC------T 128

  Fly   155 RKPLTATAAVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWV 219
            |:.|....|:..::.||.....||.:||.||..|..|...|.|..||...|....|::...:.:.
  Rat   129 RRQLAWDTAIPLVLFVWLSSAFWASLPLMGWGHYDYEPVGTCCTLDYSRGDRNFISFLFTMAFFN 193

  Fly   220 YLTPLLTIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTI--SL 282
            :|.||.....||              |...:|::          :|..:::.      ||:  .:
  Rat   194 FLVPLFITHTSY--------------RFMEQKLS----------RSGHLQVN------TTLPGRM 228

  Fly   283 WFFAWTPYTIIN-YAGIFESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLA 346
            ....|.||.::. ||.:.:...:||...:..::.||.....|.|.|         .||.:|.|..
  Rat   229 LLLGWGPYALLYLYAAVADVSFISPKLQMVPALIAKTMPTINAINY---------ALRSEMVCRG 284

  Fly   347 ---CGKDDLTSDSRTQ 359
               |.....:...|||
  Rat   285 TWQCRSAQKSKQDRTQ 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	71/311 (23%)
		TM helix 1	50..74	CDD:320207	5/23 (22%)
		TM helix 2	83..105	CDD:320207	6/32 (19%)
		TM helix 3	121..143	CDD:320207	6/24 (25%)
		TM helix 4	165..181	CDD:320207	4/15 (27%)
		TM helix 5	209..232	CDD:320207	5/22 (23%)
		TM helix 6	273..295	CDD:320207	5/24 (21%)
		TM helix 7	306..331	CDD:320207	6/24 (25%)
Rgr	XP_038950404.1	7tmA_Retinal_GPR	17..286	CDD:320200	74/316 (23%)
		TM helix 1	19..43	CDD:320200	5/23 (22%)
		TM helix 2	52..74	CDD:320200	5/21 (24%)
		TM helix 3	98..120	CDD:320200	5/21 (24%)
		TM helix 4	139..155	CDD:320200	4/15 (27%)
		TM helix 5	183..206	CDD:320200	6/36 (17%)
		TM helix 6	219..241	CDD:320200	5/27 (19%)
		TM helix 7	253..278	CDD:320200	7/33 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910