DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and opn1sw1

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_571394.1	Gene:	opn1sw1 / 30582	ZFINID:	ZDB-GENE-991109-25	Length:	336	Species:	Danio rerio

Alignment Length:	348	Identity:	93/348 - (26%)
Similarity:	166/348 - (47%)	Gaps:	40/348 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 VDPYWYQWPPLEPMW-----FGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAF 91
            |.|:..:...:.|.|     ...:|||. |:||..   |.||:::....|.||.|.|..:||::.
Zfish    14 VSPFEGEQYHIAPKWAFYLQAAFMGFVF-IVGTPM---NGIVLFVTMKYKKLRQPLNYILVNISL 74

  Fly    92 SDFMMMFTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARK 156
            :.|:........|.:....|.:.:|..||.:....||:.|.|:.||:.::|::||.||.|.....
Zfish    75 AGFIFDTFSVSQVSVCAARGYYSLGYTLCSMEAAMGSIAGLVTGWSLAVLAFERYVVICKPFGSF 139

  Fly   157 PLTATAAVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAK--DWWNRSYIIVYSLWV 219
            ......||..::..|.|..|.|..|.|||:||:|||..||||.|::.|  ::.:.||.....:..
Zfish   140 KFGQGQAVGAVVFTWIIGTACATPPFFGWSRYIPEGLGTACGPDWYTKSEEYNSESYTYFLLITC 204

  Fly   220 YLTPLLTIIFSYWHI---MKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTIS 281
            ::.|:..|||||..:   ::||||.:                 :|::.::..|.:::::.:..:.
Zfish   205 FMMPMTIIIFSYSQLLGALRAVAAQQ-----------------AESESTQKAEREVSRMVVVMVG 252

  Fly   282 LWFFAWTPY--TIINYAGIFESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPC 344
            .:...:.||  |.:.:|...|......|..| .:.|:|:::|.||::|...:.::...:.|.:
Zfish   253 SFVLCYAPYAVTAMYFANSDEPNKDYRLVAI-PAFFSKSSSVYNPLIYAFMNKQFNACIMETV-- 314

  Fly   345 LACGK--DDLTSDSRTQATAEIS 365
              .||  |:.:..|....|:.:|
Zfish   315 --FGKKIDESSEVSSKTETSSVS 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	82/296 (28%)
		TM helix 1	50..74	CDD:320207	9/23 (39%)
		TM helix 2	83..105	CDD:320207	4/21 (19%)
		TM helix 3	121..143	CDD:320207	6/21 (29%)
		TM helix 4	165..181	CDD:320207	4/15 (27%)
		TM helix 5	209..232	CDD:320207	7/22 (32%)
		TM helix 6	273..295	CDD:320207	3/23 (13%)
		TM helix 7	306..331	CDD:320207	8/24 (33%)
opn1sw1	NP_571394.1	7tm_4	39..310	CDD:304433	81/292 (28%)
opn1sw1	NP_571394.1	7tm_1	48..299	CDD:278431	75/268 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910