DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and opn1mw1

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_571328.2	Gene:	opn1mw1 / 30503	ZFINID:	ZDB-GENE-990604-42	Length:	349	Species:	Danio rerio

Alignment Length:	349	Identity:	99/349 - (28%)
Similarity:	166/349 - (47%)	Gaps:	35/349 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PYWY-QWPPLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMM 97
            ||.| |:...||..|..:.|.:.:|.......|.:.:.:....|.||.|.|..:|||||:..:|:
Zfish    23 PYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMV 87

  Fly    98 FTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATA 162
            ...|.........|...:||..|.:.|.|.:|.|.|::||:.::|.:||.|:.|.|.....:|..
Zfish    88 IFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANH 152

  Fly   163 AVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFA--KDWWNRSYIIVYSLWVYLTPLL 225
            |:..:...|.:..:.|:.|||||:||:|||..|:||.||:.  .::.|.||::......:..|:.
Zfish   153 AMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVT 217

  Fly   226 TIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPY 290
            ||.|:|..::..|.|              |:.:..|::.::..|.::.::.:..:..:.|||.||
Zfish   218 TIFFTYGSLVCTVKA--------------AAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPY 268

  Fly   291 T------IINYAGIFESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGK 349
            .      ..|....|.:..::     ..:.|:|.:||.|||:|.|.:.:::..:   :..|.|||
Zfish   269 ASFAAWIFFNRGAAFSAQAMA-----VPAFFSKTSAVFNPIIYVLLNKQFRSCM---LNTLFCGK 325

  Fly   350 ----DDLTSDSRTQATAEISESQA 369
                ||.:|...|..|...|.|.|
Zfish   326 SPLGDDESSSVSTSKTEVSSVSPA 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	80/297 (27%)
		TM helix 1	50..74	CDD:320207	3/23 (13%)
		TM helix 2	83..105	CDD:320207	8/21 (38%)
		TM helix 3	121..143	CDD:320207	7/21 (33%)
		TM helix 4	165..181	CDD:320207	2/15 (13%)
		TM helix 5	209..232	CDD:320207	6/22 (27%)
		TM helix 6	273..295	CDD:320207	5/27 (19%)
		TM helix 7	306..331	CDD:320207	9/24 (38%)
opn1mw1	NP_571328.2	Rhodopsin_N	2..37	CDD:287397	6/13 (46%)
		7tm_4	45..>222	CDD:304433	56/176 (32%)
		7tm_1	55..306	CDD:278431	76/269 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..349		7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48050
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920