DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rh6 and OPN3

DIOPT Version :9

Sequence 1:NP_524368.5 Gene:Rh6 / 41889 FlyBaseID:FBgn0019940 Length:369 Species:Drosophila melanogaster
Sequence 2:NP_055137.2 Gene:OPN3 / 23596 HGNCID:14007 Length:402 Species:Homo sapiens


Alignment Length:312 Identity:90/312 - (28%)
Similarity:155/312 - (49%) Gaps:25/312 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 PPLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSD-----FMMMFT 99
            |...|..:..:..::..:|.:.:..|.:|:.::...:.||||:::.:||::.||     |.:.||
Human    34 PLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFT 98

  Fly   100 MFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAV 164
             |...:.||    |:.....|...|..|||||.|||.::|::||:||..:|..   :.:..:.|.
Human    99 -FVSCLRNG----WVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHA---RVINFSWAW 155

  Fly   165 LRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWVYLTPLLTIIF 229
            ..:..:|....|||..||.|||||:.:.:...|..|:.:||..:.|:::...|...:.||..|..
Human   156 RAITYIWLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAH 220

  Fly   230 SYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTIIN 294
            .|.||:.::    :.:|      .|..|:..:..|....|.||||:....|..:...|.||.:|.
Human   221 CYGHILYSI----RMLR------CVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVIC 275

  Fly   295 YAGIFESMHL-SPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCL 345
            :..:....|| :|..:|...:|||:|.|.||::|.....|:::.|.:.: ||
Human   276 FLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLL-CL 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rh6NP_524368.5 7tmA_photoreceptors_insect 48..338 CDD:320207 85/295 (29%)
TM helix 1 50..74 CDD:320207 3/23 (13%)
TM helix 2 83..105 CDD:320207 8/26 (31%)
TM helix 3 121..143 CDD:320207 10/21 (48%)
TM helix 4 165..181 CDD:320207 4/15 (27%)
TM helix 5 209..232 CDD:320207 5/22 (23%)
TM helix 6 273..295 CDD:320207 7/21 (33%)
TM helix 7 306..331 CDD:320207 10/24 (42%)
OPN3NP_055137.2 7tmA_Encephalopsin 58..316 CDD:320206 83/275 (30%)
TM helix 2 76..103 CDD:320206 8/27 (30%)
TM helix 3 114..144 CDD:320206 15/29 (52%)
TM helix 4 152..174 CDD:320206 6/21 (29%)
TM helix 5 199..229 CDD:320206 8/29 (28%)
TM helix 6 248..278 CDD:320206 10/29 (34%)
TM helix 7 288..313 CDD:320206 10/24 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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