Protein Alignment Rh6 and Opn1mw

DIOPT Version :10

• Sequence 1: NP_524368.5
• Gene: Rh6 / 41889
• FlyBaseID: FBgn0019940
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_032132.1
• Gene: Opn1mw / 14539
• MGIID: 1097692
• Length: 359
• Species: Mus musculus
• Alignment Length: 384
• Identity: 97/384 - (25%)
• Similarity: 165/384 - (42%)
• Gaps: 58/384 - (15%)

  Fly     3 SLHPPSFAYMR--------DGRNLSLAESVPAEIMHMVDPYWYQWPPLEPMWFGIIGFVIAILGT 59
            |.|...|.|..        :|.|..:|   |..:.|           |...|..::  |:|
Mouse    17 STHASIFTYTNSNSTKGPFEGPNYHIA---PRWVYH-----------LTSTWMILV--VVA---- 61

  Fly    60 MSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFPPVVLNGFYGTWIMGPFLCELYG 124
             |:..|.:|:......|.||.|.|..:||||.:|...........|:|..||.:::|..||.:.|
Mouse    62 -SVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLAETIIASTISVVNQIYGYFVLGHPLCVIEG 125

  Fly   125 MFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAVLRLMVVWTICGAWALMPLFGWNRYV 189
            ...||.|...:||:.:|:::|:.|:.|........|..|.:.::..|.....|...|:|||:||.
Mouse   126 YIVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLATVGIVFSWVWAAIWTAPPIFGWSRYW 190

  Fly   190 PEGNMTACGTDYFAKDWWN--RSYIIVYSLWVYLTPLLTIIFSY---WHIMKAVAAHEKAMREQA 249
            |.|..|:||.|.|:...:.  :||::|..:...:.||..|:..|   |..::|||..:|
Mouse   191 PYGLKTSCGPDVFSGTSYPGVQSYMMVLMVTCCIFPLSIIVLCYLQVWLAIRAVAKQQK------ 249

  Fly   250 KKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTIINYAGIFESMH----LSPLSTI 310
                       |::.::..|.::.::.:..:..:...|.|||   :...|.:.|    ..||...
Mouse   250 -----------ESESTQKAEKEVTRMVVVMVFAYCLCWGPYT---FFACFATAHPGYAFHPLVAS 300

  Fly   311 CGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGKDDLTSDSRTQATAEISESQA 369
            ..|.|||:..:.|||:|...:.:::..:............:|:|.|:|:.::..|.|.|
Mouse   301 LPSYFAKSATIYNPIIYVFMNRQFRNCILHLFGKKVDDSSELSSTSKTEVSSVSSVSPA 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	79/298 (27%)
		TM helix 1	49..75	CDD:320207	5/25 (20%)
		TM helix 2	82..108	CDD:320207	7/25 (28%)
		TM helix 3	120..150	CDD:320207	10/29 (34%)
		TM helix 4	161..181	CDD:320207	3/19 (16%)
		TM helix 5	208..237	CDD:320207	8/33 (24%)
		TM helix 6	267..297	CDD:320207	5/29 (17%)
		TM helix 7	306..331	CDD:320207	10/24 (42%)
Opn1mw	NP_032132.1	Required for 11-cis-retinal regeneration. /evidence=ECO:0000250|UniProtKB:P04001	12..38		4/20 (20%)
		7tm_GPCRs	37..328	CDD:475119	86/331 (26%)
		TM helix 1	51..75	CDD:320209	6/30 (20%)
		TM helix 2	84..106	CDD:320209	6/21 (29%)
		TM helix 3	122..144	CDD:320209	7/21 (33%)
		TM helix 4	166..182	CDD:320209	2/15 (13%)
		TM helix 5	212..235	CDD:320209	6/22 (27%)
		TM helix 6	262..284	CDD:320209	4/24 (17%)
		TM helix 7	296..321	CDD:320209	10/24 (42%)