DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rh6 and tmtops

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001304832.1	Gene:	tmtops / 100488877	XenbaseID:	XB-GENE-1018915	Length:	382	Species:	Xenopus tropicalis

Alignment Length:	280	Identity:	78/280 - (27%)
Similarity:	141/280 - (50%)	Gaps:	20/280 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 VIAI-LGTMSLAG---NFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFPPVVLNGFYGTW 113
            |:|: ||.:.:.|   |..|:.||.....:|||.||.::|::.||.::.....|...::...|.|
Frog    38 VVAVCLGCILVLGSLYNSFVLLIFVKFTAIRTPINMILLNISVSDLLVCIFGTPFSFVSSVSGGW 102

  Fly   114 IMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAVLRLMVVWTICGAWA 178
            ::|...|:.||...||||.||:.|:::::|:||..::|...........:.|.::|.|.....|.
Frog   103 LLGQQGCKWYGFCNSLFGLVSMISLSMLSYERYLTVLKCTKADMTDYKKSWLCIIVSWLYSLCWT 167

  Fly   179 LMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWVYLTPLLTIIFSYWHIMKAVAAHEK 243
            |.||.||:.|..|.:.|.|...:.:|...|.|||:...|:..:.||..:||.|.||::.:
Frog   168 LPPLIGWSSYGLESSGTTCSVVWHSKSSNNISYIVCLFLFCLVLPLFIMIFCYGHIVRVI----- 227

  Fly   244 AMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTIINYAGIF-ESMHLSPL 307
              |.|..::|:.:.:..|.        :|..:.:..::.:...|.||.:::....| :...::|.
Frog   228 --RGQVCRINMTTAQKREH--------RLLFMVVCMVTCYLLCWMPYGLVSLMTAFGKPGMITPT 282

  Fly   308 STICGSVFAKANAVCNPIVY 327
            .:|..|:.||::...||::|
Frog   283 VSIIPSILAKSSTFINPLIY 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	78/280 (28%)
		TM helix 1	50..74	CDD:320207	9/24 (38%)
		TM helix 2	83..105	CDD:320207	6/21 (29%)
		TM helix 3	121..143	CDD:320207	9/21 (43%)
		TM helix 4	165..181	CDD:320207	5/15 (33%)
		TM helix 5	209..232	CDD:320207	8/22 (36%)
		TM helix 6	273..295	CDD:320207	3/21 (14%)
		TM helix 7	306..331	CDD:320207	8/22 (36%)
tmtops	NP_001304832.1	7tm_1	54..302	CDD:278431	72/262 (27%)
tmtops	NP_001304832.1	7tm_4	<119..319	CDD:304433	52/199 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910