DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and opn1sw

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001119548.1	Gene:	opn1sw / 100125215	XenbaseID:	XB-GENE-993052	Length:	349	Species:	Xenopus tropicalis

Alignment Length:	342	Identity:	91/342 - (26%)
Similarity:	166/342 - (48%)	Gaps:	39/342 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LEPMWFGIIGFVIAIL--GTMSLAG---NFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMM-MFTM 100
            :.|.|    .|.:..|  |.:.|.|   |.||:.:....|.||.|.|..:||:|...|:| :|::
Frog    28 IAPKW----AFTLQALFMGAVFLFGAPLNLIVLVVTMKYKKLRQPLNYILVNIAVGGFLMCIFSI 88

  Fly   101 FPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAVL 165
            | ||.::...|.:.:|...|.:....|::.|.|:.||:..:|::||.||.|.|.....:::.|:.
Frog    89 F-PVFISSSKGYFFLGKVACNIDAFIGTVSGLVTGWSLAFLAFERYIVICKPMGNFTFSSSHAMA 152

  Fly   166 RLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWV--YLTPLLTII 228
            .::..|.|....::.|.|||:||:|||...:||.|::......||....:.:::  ::.||..|.
Frog   153 VVICTWIIGIGVSVPPFFGWSRYMPEGLQCSCGPDWYTVGTKYRSEYYTWFIFIFCFVMPLTMIC 217

  Fly   229 FSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTII 293
            |||..::.|:.|             ||:.:...|...|| |.:::::.:..:..:...:.||..:
Frog   218 FSYGRLLGALRA-------------VAAQQQESASTQKA-EREVSRMVVVMVGSFCLCYVPYAAM 268

  Fly   294 NYAGIFESMHLSPLSTI-CGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGKDDLTSDSR 357
            ....:....|...|..: ..:.|:|:..|.|||:|...:.:::..:.|.:    ||: .:|.||.
Frog   269 AMYMVTNRDHGLDLRLVTIPAFFSKSACVYNPIIYSFMNKQFRGCIMETV----CGR-PMTDDSS 328

  Fly   358 TQATAE------ISESQ 368
            ..:|::      :|.||
Frog   329 VSSTSQKTEVSTVSSSQ 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	79/298 (27%)
		TM helix 1	50..74	CDD:320207	8/28 (29%)
		TM helix 2	83..105	CDD:320207	9/22 (41%)
		TM helix 3	121..143	CDD:320207	5/21 (24%)
		TM helix 4	165..181	CDD:320207	2/15 (13%)
		TM helix 5	209..232	CDD:320207	7/24 (29%)
		TM helix 6	273..295	CDD:320207	2/21 (10%)
		TM helix 7	306..331	CDD:320207	8/25 (32%)
opn1sw	NP_001119548.1	7tmA_SWS1_opsin	35..314	CDD:320204	78/293 (27%)
		TM helix 1	36..62	CDD:320204	7/25 (28%)
		TM helix 2	69..96	CDD:320204	10/27 (37%)
		TM helix 3	107..137	CDD:320204	10/29 (34%)
		TM helix 4	148..170	CDD:320204	4/21 (19%)
		TM helix 5	197..227	CDD:320204	7/29 (24%)
		TM helix 6	242..272	CDD:320204	5/30 (17%)
		TM helix 7	282..307	CDD:320204	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910