DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and opn6a

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001096345.1	Gene:	opn6a / 100124934	XenbaseID:	XB-GENE-5872637	Length:	400	Species:	Xenopus tropicalis

Alignment Length:	361	Identity:	89/361 - (24%)
Similarity:	157/361 - (43%)	Gaps:	66/361 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSD-----------F 94
            ||......|||..:..||.:|..||.||:::....:....|::....|||.||           .
Frog    24 PLTEQGETIIGIYLLALGWLSWFGNSIVIFVLYKQRANLLPTDYLTFNLAVSDASTSVFGYSRGI 88

  Fly    95 MMMFTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLT 159
            :.:|.:|..   :||..|.|   :.|::.|....|||..||.::|||:..||   :||.  .|..
Frog    89 IEIFNVFRD---DGFLITSI---WTCQVDGFLTLLFGLASINTLTLISVTRY---IKGC--HPQR 142

  Fly   160 AT-----AAVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAKDWWN--RSYIIVYSL 217
            |.     :..:.|.::|.....|::.||.||..| .:.....|..|:....:..  :||||...:
Frog   143 ANCISNGSITISLALIWIAALFWSVAPLLGWGSY-RDRMYGTCEIDWTKASFSTIYKSYIISIFI 206

  Fly   218 WVYLTPLLTIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISL 282
            ..:..|::.::|.|..|:..|           |.....:.....:::.:.:|..:.:|::...:.
Frog   207 CCFFLPVMVMVFCYVSIINTV-----------KSSRALTSEGDLSERQRKMERDVTRVSVVICTA 260

  Fly   283 WFFAWTPYTIINYAGIFESM------HLSPLSTICGSVFAKANAVCNPIVY-GLSHPKYKQVLRE 340
            :..||:||.:|       ||      ::..|::|..::|||:.:..||::| |:| .|:::.|..
Frog   261 FIVAWSPYAVI-------SMWSACGYYVPSLTSILAALFAKSASFYNPLIYFGMS-SKFRKDLCV 317

  Fly   341 KMPCLACGKDDLT----------SDSRTQATAEISE 366
            .:||....||.:.          |..|.:...||.:
Frog   318 VLPCAKAQKDPVKLKRYKDKKQGSAPRAREQTEIEQ 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	78/314 (25%)
		TM helix 1	50..74	CDD:320207	9/23 (39%)
		TM helix 2	83..105	CDD:320207	7/32 (22%)
		TM helix 3	121..143	CDD:320207	9/21 (43%)
		TM helix 4	165..181	CDD:320207	3/15 (20%)
		TM helix 5	209..232	CDD:320207	6/22 (27%)
		TM helix 6	273..295	CDD:320207	6/21 (29%)
		TM helix 7	306..331	CDD:320207	9/25 (36%)
opn6a	NP_001096345.1	7tmA_Opsin5_neuropsin	31..315	CDD:320202	78/314 (25%)
		TM helix 1	32..58	CDD:320202	10/25 (40%)
		TM helix 2	65..92	CDD:320202	5/26 (19%)
		TM helix 3	108..138	CDD:320202	13/32 (41%)
		TM helix 4	151..169	CDD:320202	3/17 (18%)
		TM helix 5	197..227	CDD:320202	8/29 (28%)
		TM helix 6	245..275	CDD:320202	9/36 (25%)
		TM helix 7	283..308	CDD:320202	9/24 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000