DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh6 and opn1lw

DIOPT Version :9

Sequence 1:	NP_524368.5	Gene:	Rh6 / 41889	FlyBaseID:	FBgn0019940	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001096331.1	Gene:	opn1lw / 100124917	XenbaseID:	XB-GENE-955009	Length:	365	Species:	Xenopus tropicalis

Alignment Length:	338	Identity:	88/338 - (26%)
Similarity:	158/338 - (46%)	Gaps:	35/338 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LEPMW-FGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFPPVV 105
            :.|.| :.|....:..:...|:..|.:|:......|.||.|.|..:||:|.:|...........|
Frog    46 IAPRWVYNISSLWMIFVVLASVFTNGLVLVATLKFKKLRHPLNWILVNMAIADLGETVIASTISV 110

  Fly   106 LNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAVLRLMVV 170
            .|..:|.:::|..:|.|.|...|:.|..::||:|:||::|:.|:.|...........|...::..
Frog   111 CNQIFGYFVLGHPMCILEGYTVSVCGIAALWSLTVIAWERWFVVCKPFGNIKFDGKLAATGIIFS 175

  Fly   171 WTICGAWALMPLFGWNRYVPEGNMTACGTDYF--AKDWWNRSYIIVYSLWVYLTPLLTIIFSYWH 233
            |.....|...|:|||:||.|.|..|:||.|.|  :.|...:||::|..:...:.||..|:..|.|
Frog   176 WVWAAGWCAPPIFGWSRYWPHGLKTSCGPDVFSGSSDPGVQSYMLVLMITCCIIPLAIIVLCYMH 240

  Fly   234 I---MKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTIIN- 294
            :   ::.||..:|                 |::.::..|.:::::.:..|..:.|.|.|||...
Frog   241 VWLTIRQVAQQQK-----------------ESESTQKAEREVSRMVVVMIIAYIFCWGPYTFFAC 288

  Fly   295 YAGIFESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGK--DD---LTS 354
            :|......:..||:....:.|||:..:.|||:|...:.:::..:.:..     ||  ||   ::|
Frog   289 FAAFNPGYNFHPLAAAMPAYFAKSATIYNPIIYVFMNRQFRNCIYQLF-----GKKVDDGSEVSS 348

  Fly   355 DSRTQATAEISES 367
            .|||:.:: :|.|
Frog   349 TSRTEVSS-VSNS 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh6	NP_524368.5	7tmA_photoreceptors_insect	48..338	CDD:320207	76/295 (26%)
		TM helix 1	50..74	CDD:320207	3/23 (13%)
		TM helix 2	83..105	CDD:320207	5/21 (24%)
		TM helix 3	121..143	CDD:320207	8/21 (38%)
		TM helix 4	165..181	CDD:320207	2/15 (13%)
		TM helix 5	209..232	CDD:320207	6/22 (27%)
		TM helix 6	273..295	CDD:320207	6/22 (27%)
		TM helix 7	306..331	CDD:320207	9/24 (38%)
opn1lw	NP_001096331.1	7tmA_LWS_opsin	41..332	CDD:320209	78/302 (26%)
		TM helix 1	54..80	CDD:320209	4/25 (16%)
		TM helix 2	87..114	CDD:320209	7/26 (27%)
		TM helix 3	125..155	CDD:320209	12/29 (41%)
		TM helix 4	166..188	CDD:320209	4/21 (19%)
		TM helix 5	215..245	CDD:320209	8/29 (28%)
		TM helix 6	260..290	CDD:320209	7/29 (24%)
		TM helix 7	300..325	CDD:320209	9/24 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910