Sequence 1: | NP_996218.1 | Gene: | AdamTS-A / 41887 | FlyBaseID: | FBgn0286071 | Length: | 1688 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001381461.1 | Gene: | THSD4 / 79875 | HGNCID: | 25835 | Length: | 1018 | Species: | Homo sapiens |
Alignment Length: | 1051 | Identity: | 241/1051 - (22%) |
---|---|---|---|
Similarity: | 365/1051 - (34%) | Gaps: | 311/1051 - (29%) |
- Green bases have known domain annotations that are detailed below.
Fly 633 WS-WSKCSRHFVSEFLEKTDKSCLETSV---GAHIPYGTERLPGE--IYSLDAQCQLSFGNDFGY 691
Fly 692 CPTDEECKRLWCNRTSGNSNEQCASSNLPWADGTPCGSSGHWCQRGKCVSNKHGYGRQVNGGWGP 756
Fly 757 W-------TPFTPCSL---------TCGGGVQESRRECNQP---VPENGGKY------------- 789
Fly 790 ----------------------------------------------------CTGSRKKYRSCNT 802
Fly 803 HQCPPGSMDPREQQCYAMNGRNMNIPGVNPDTKWVPKYE---KDACKLFCRMDMKVTYFMLKSMV 864
Fly 865 TDGTSCAVDSFDKCVNGICRPAGCDNELNSIAKLDKCGVCEGRNDTCHEVTG---NLLVSNLLGL 926
Fly 927 NDGNEPNKTLYYVTRIPKGASNIIITQRGYPDQNFIVLTDDRDNELLNGKFLKTYPLKFVYAGVT 991
Fly 992 MQYTGSSSVVEQVNTTYSWKLSRDLIVQIISLDVSPSKRQDTVLLSYSYTI--------DKPP-- 1046
Fly 1047 ------------------------------DYEAEV-EIY------------------------- 1055
Fly 1056 -------------RWEMQAPSNCDSLC-EGRSHRLPACISTTQGVKVAPQFCDKSAMPKIDDRAC 1106
Fly 1107 NT-DCRLNLTVTSISECSAACGELGTREKTYACVQTFTNMQRSNIVD------------MSYCKL 1158
Fly 1159 KFDVAYHEECREGCW-VLSEWSTCSKSCGTGSQQREAHCYLH-NSRVSDDLCNPRTKPHLNTLIG 1221
Fly 1222 ICNTESCPTYTKSPNALAVSNWVIGEWGE-CNEWC---EKTRSVSC--SHPYGI---GCGSRKPK 1277
Fly 1278 DVRKC----CHIK---YTSDWTDCSVQCGEGVKRKKQSCTRVYKPDVPGTRKRRVY--VDESYCI 1333
Fly 1334 SRKVHRPKLRTTTKSCRI---NCKWNASDWRRCPADCSEEYQTRDVRCESFQGDGVEDKHCDAKK 1395
Fly 1396 RPSKRRICN--NCVRRQSRVISQC-----NCEGVEKRRDFCFNSHKGRIACPTRARVERHSCTPP 1453
Fly 1454 PHCRRRSAIGS 1464 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
AdamTS-A | NP_996218.1 | Pep_M12B_propep | 286..394 | CDD:279848 | |
ZnMc_ADAMTS_like | 455..655 | CDD:239801 | 8/22 (36%) | ||
Reprolysin | 457..655 | CDD:279729 | 8/22 (36%) | ||
Salp15 | <696..745 | CDD:288931 | 9/48 (19%) | ||
TSP1 | 754..806 | CDD:214559 | 18/135 (13%) | ||
ADAM_spacer1 | 937..1042 | CDD:283607 | 25/104 (24%) | ||
TSP1 | 1172..1229 | CDD:214559 | 15/58 (26%) | ||
GON | 1495..1687 | CDD:285848 | |||
THSD4 | NP_001381461.1 | TSP1 | 58..>95 | CDD:214559 | 13/36 (36%) |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 111..235 | 26/137 (19%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 254..279 | 0/24 (0%) | |||
ADAM_spacer1 | 412..528 | CDD:368694 | 31/133 (23%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 534..623 | 6/88 (7%) | |||
TSP1_ADAMTS | 627..676 | CDD:408800 | 10/48 (21%) | ||
TSP1_ADAMTS | 680..736 | CDD:408800 | 18/65 (28%) | ||
TSP1_ADAMTS | 739..793 | CDD:408800 | 16/64 (25%) | ||
TSP1_ADAMTS | 797..850 | CDD:408800 | 17/52 (33%) | ||
TSP1_ADAMTS | 856..912 | CDD:408800 | 14/69 (20%) | ||
TSP1_ADAMTS | 916..967 | CDD:408800 | 16/52 (31%) | ||
PLAC | 975..1005 | CDD:400844 | 10/38 (26%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3538 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |