DRSC/TRiP Functional Genomics Resources

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Protein Alignment AdamTS-A and Wfikkn1

DIOPT Version :9

Sequence 1:NP_996218.1 Gene:AdamTS-A / 41887 FlyBaseID:FBgn0286071 Length:1688 Species:Drosophila melanogaster
Sequence 2:NP_001123248.1 Gene:Wfikkn1 / 363555 RGDID:1565835 Length:552 Species:Rattus norvegicus


Alignment Length:414 Identity:73/414 - (17%)
Similarity:109/414 - (26%) Gaps:176/414 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly   631 HPW--SWSKCSRHFV-SEFLEKTDKSC-----LETSVGAHIPYGTERLPGEIYSLDAQCQLSFGN 687
            |.|  :.|.|.|... .:....::|.|     |::.|.|..|.|....|    ...|.|:     
  Rat    43 HLWVDAQSTCERECTRDQDCAASEKCCTNVCGLQSCVAARFPSGGPATP----ETAASCE----- 98

  Fly   688 DFGYCPTDEECKRLW-------C-NRTSGNSNEQCASSNLPWADGTPCGSSGHWCQRG---KCVS 741
            || .||.......:|       | :|.....:..|||..|.:.:  .|......|.||   ..|.
  Rat    99 DF-QCPQQGSNCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYN--RCYMDAEACLRGLHLHVVP 160

  Fly   742 NKHGYGRQVNGGWGPWTPFTP--CSLTCGGGVQESRRECNQPVPEN---GGKYCTGSRKKYRSCN 801
            .||..      .|.|.:|..|  .:....|.........|.|.|:.   ||   |.|    ..|:
  Rat   161 CKHIL------SWPPSSPGPPETTARPTPGAAPMPPALYNSPSPQAVHVGG---TAS----LHCD 212

  Fly   802 THQCPPGSMDPREQQ---------------------------------------CYAMNGRNM-- 825
            ....||.::...:|.                                       |.|.|...:  
  Rat   213 VSGRPPPAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNAQLEDAGLYTCTARNAAGLLR 277

  Fly   826 ---------------NIPGV------NPDTK------------WVPKYEKDACKLFCRMDMKVTY 857
                           ..|||      .|||:            |....::.:|..|         
  Rat   278 ADFPLSVLQRATTQDRDPGVLALAECQPDTQACVGPPTPHHVLWRFDPQRGSCMTF--------- 333

  Fly   858 FMLKSMVTDGTSCAVDSFDKC----------------VNGICRP-------------------AG 887
               .::..||.:...::::.|                |.|.|:.                   :|
  Rat   334 ---PALKCDGAARGFETYEACQQACVRGPGDVCALPPVQGPCQGWEPRWAYSPLLQQCHPFIYSG 395

  Fly   888 CDNELNSIAKLDKCGVCEGRNDTC 911
            |:...|:....:.|      .|.|
  Rat   396 CEGNSNNFESRESC------EDAC 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdamTS-ANP_996218.1 Pep_M12B_propep 286..394 CDD:279848
ZnMc_ADAMTS_like 455..655 CDD:239801 7/31 (23%)
Reprolysin 457..655 CDD:279729 7/31 (23%)
Salp15 <696..745 CDD:288931 13/59 (22%)
TSP1 754..806 CDD:214559 13/56 (23%)
ADAM_spacer1 937..1042 CDD:283607
TSP1 1172..1229 CDD:214559
GON 1495..1687 CDD:285848
Wfikkn1NP_001123248.1 WAP 34..80 CDD:278522 8/36 (22%)
KAZAL_FS 124..159 CDD:238052 8/36 (22%)
I-set 196..284 CDD:254352 13/94 (14%)
Ig_3 204..284 CDD:143242 11/86 (13%)
KU 311..356 CDD:294074 6/56 (11%)
KU 361..413 CDD:197529 8/57 (14%)
NTR_like 431..541 CDD:295338
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3538
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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