DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdamTS-A and wu:fb59d01

DIOPT Version :9

Sequence 1:	NP_996218.1	Gene:	AdamTS-A / 41887	FlyBaseID:	FBgn0286071	Length:	1688	Species:	Drosophila melanogaster
Sequence 2:	NP_001373281.1	Gene:	wu:fb59d01 / 322379	ZFINID:	ZDB-GENE-030131-1098	Length:	211	Species:	Danio rerio

Alignment Length:	186	Identity:	39/186 - (20%)
Similarity:	57/186 - (30%)	Gaps:	71/186 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   666 GTERLPGEIYSLDAQCQLSFGNDFGYCPTDEECKRLWCNRTSGNSN-----EQCASSNLPWADGT 725
            |||::....|.|.|                :.|...:...|.||.|     ::|..:..|.|
Zfish    36 GTEKIKKYFYDLQA----------------DSCVPFYFKGTGGNGNRFDSDKECVKACSPKA--- 81

  Fly   726 PCGSSGHWCQRGKCVSNKHGYGRQVNGGWGPWTPFTPCSLTCGGGVQESRRECNQPVPENGGKYC 790
                                  .|:.    |....:.||:....|.      |....|    .|.
Zfish    82 ----------------------LQIY----PTDETSICSMEMDEGT------CFALFP----MYY 110

  Fly   791 TGSRKK------YRSCNTHQCPPGSMDPREQQCYAMNGRNM---NIPGVNPDTKWV 837
            ..:.:|      ||.|..:.....|.:..:|.|.|.:||.|   ::|  |||.|.|
Zfish   111 YNAEEKICRMFIYRGCRGNANRFESREECQQTCLARSGRLMGAADLP--NPDEKTV 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdamTS-A	NP_996218.1	Pep_M12B_propep	286..394	CDD:279848
		ZnMc_ADAMTS_like	455..655	CDD:239801
		Reprolysin	457..655	CDD:279729
		Salp15	<696..745	CDD:288931	8/53 (15%)
		TSP1	754..806	CDD:214559	11/57 (19%)
		ADAM_spacer1	937..1042	CDD:283607
		TSP1	1172..1229	CDD:214559
		GON	1495..1687	CDD:285848
wu:fb59d01	NP_001373281.1	Kunitz_BPTI	27..77	CDD:394972	12/56 (21%)
wu:fb59d01	NP_001373281.1	Kunitz_BPTI	92..143	CDD:394972	12/60 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900