DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdamTS-A and si:dkeyp-73b11.8

DIOPT Version :9

Sequence 1:	NP_996218.1	Gene:	AdamTS-A / 41887	FlyBaseID:	FBgn0286071	Length:	1688	Species:	Drosophila melanogaster
Sequence 2:	NP_001373612.1	Gene:	si:dkeyp-73b11.8 / 100333708	ZFINID:	ZDB-GENE-131120-176	Length:	230	Species:	Danio rerio

Alignment Length:	193	Identity:	43/193 - (22%)
Similarity:	66/193 - (34%)	Gaps:	64/193 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   562 LAELGTV--CSSSSCSIVQDTGLPTAFTMAHELGH----ILNMNHD-DDDKCMPYVTRQNNNKVL 619
            :.|||.:  ..:.:.:|...|..|.|.|:..:.|.    ::.|.:| |.|.|.|:  |.|..
Zfish     1 MRELGIILFIFALNHNIQAQTRKPEACTLKQDEGTGNDVVVYMYYDADKDSCYPF--RYNGE--- 60

  Fly   620 HIMSSVMGIHMHPWSWSKCSRHFVSEFLEKTDKSCLETSVGAH-----IPYGTER---LPGEIYS 676
                            ...|..|:      |:|.|:...  :|     .|...::   ||.|
Zfish    61 ----------------GGNSNRFI------TEKQCMRNC--SHRADQLFPMDGKQICVLPRE--- 98

  Fly   677 LDAQCQLSFGN--DFGYCPTDEECKRLWCNRTSGNSN-----EQCASSNLPWADGTPCGSSGH 732
             ..||   ||:  .:.|.|....||..:.....||.|     .:|.::....||      .||
Zfish    99 -PGQC---FGHYLRYYYSPEHHTCKPFYWTGCVGNGNRFLSLNRCNATCYNSAD------KGH 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdamTS-A	NP_996218.1	Pep_M12B_propep	286..394	CDD:279848
		ZnMc_ADAMTS_like	455..655	CDD:239801	21/99 (21%)
		Reprolysin	457..655	CDD:279729	21/99 (21%)
		Salp15	<696..745	CDD:288931	10/42 (24%)
		TSP1	754..806	CDD:214559
		ADAM_spacer1	937..1042	CDD:283607
		TSP1	1172..1229	CDD:214559
		GON	1495..1687	CDD:285848
si:dkeyp-73b11.8	NP_001373612.1	Kunitz_BPTI	26..77	CDD:394972	16/77 (21%)
si:dkeyp-73b11.8	NP_001373612.1	KU	92..143	CDD:238057	15/57 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900