Protein Alignment Act88F and ACTRT3

DIOPT Version :10

• Sequence 1: NP_524367.1
• Gene: Act88F / 41885
• FlyBaseID: FBgn0000047
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_115876.3
• Gene: ACTRT3 / 84517
• HGNCID: 24022
• Length: 372
• Species: Homo sapiens
• Alignment Length: 368
• Identity: 183/368 - (49%)
• Similarity: 263/368 - (71%)
• Gaps: 3/368 - (0%)

  Fly     9 LVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIE 73
            :||||||||.|||.||...|:.::|:|:||.:.|. ....|..:..|||:||..|..|.:.||:|
Human     8 VVIDNGSGMIKAGVAGCREPQFIYPNIIGRAKGQS-RAAQGGLELCVGDQAQDWRSSLFISYPVE 71

  Fly    74 HGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQ 138
            .|:||:|:|||.:|.|.:...|::.|.:.|||:||..|||.|||:::|::.||....||.|::||
Human    72 RGLITSWEDMEIMWKHIYDYNLKLKPCDGPVLITEPALNPLANRQQITEMFFEHLGVPAFYMSIQ 136

  Fly   139 AVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTDYLMKILTERGYSFTT 203
            |||:|:|:|.|||:||:||.||:.:|||:||:.|||.:.:|||||.|||:|||.::...|....:
Human   137 AVLALFAAGFTTGLVLNSGAGVTQSVPIFEGYCLPHGVQQLDLAGLDLTNYLMVLMKNHGIMLLS 201

  Fly   204 TAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPEALFQPSFL 268
            .::|:||.||||..||||:::|:||  |.....|||.|:||||:||.:.::.|.||||||.|..:
Human   202 ASDRKIVEDIKESFCYVAMNYEEEM--AKKPDCLEKVYQLPDGKVIQLHDQLFSCPEALFSPCHM 264

  Fly   269 GMESCGIHETVYNSIMKCDVDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAP 333
            .:|:.||.:..::||||||..:|...::|.:|:||:|.:||:..|:.|:|..:||:...:::|||
Human   265 NLEAPGIDKICFSSIMKCDTGLRNSFFSNIILAGGSTSFPGLDKRLVKDIAKVAPANTAVQVIAP 329

  Fly   334 PERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376
            ||||.|||:|||||||||.||.|||:..|:.|.||.|||::||
Human   330 PERKISVWMGGSILASLSAFQDMWITAAEFKEVGPNIVHQRCF 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act88F	NP_524367.1	ASKHA_NBD_actin	8..371	CDD:466823	178/361 (49%)
ACTRT3	NP_115876.3	ASKHA_NBD_actin_Arp-T1-3	7..363	CDD:466848	176/357 (49%)