Protein Alignment Act88F and ACTL8

DIOPT Version :10

• Sequence 1: NP_524367.1
• Gene: Act88F / 41885
• FlyBaseID: FBgn0000047
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_110439.2
• Gene: ACTL8 / 81569
• HGNCID: 24018
• Length: 366
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 126/378 - (33%)
• Similarity: 194/378 - (51%)
• Gaps: 36/378 - (9%)

  Fly     6 AGALVIDNGSGMCKAGFAGDDAPRAVFPSIVG--------RPRHQGVMVGMG----QKDSYVGDE 58
            |..::||:|||..|||.||.:.|:.|||:||.        .|.:....|.:|    ..|
Human     3 ARTVIIDHGSGFLKAGTAGWNEPQMVFPNIVNYLPCKENPGPSYARRRVSLGIDICHPD------ 61

  Fly    59 AQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQI 123
                    |..||||.|.|.||:.::.:|.....|..| ..|..||::||.||...|:|:||.:|
Human    62 --------TFSYPIERGRILNWEGVQYLWSFVLENHRR-EQEVPPVIITETPLREPADRKKMLEI 117

  Fly   124 MFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTD 188
            :||..:.|::.:|.|..:||||||..||:|:|||.|::...|.::|..||.:...|:.||:||:.
Human   118 LFELLHVPSVLLADQLQMSLYASGLLTGVVVDSGYGLTRVQPFHQGRPLPASGKTLEFAGQDLSA 182

  Fly   189 YLMKILTERGYSFTTTAEREIVRDIKEKLCYV------ALDFEQEMATAAASTSLEKSYELPDGQ 247
            ||:|.|.:.........:.|.|...:...|||      ||||.:...:|...::   :|:||||.
Human   183 YLLKSLFKEDCDRRCLFQLETVAVTQMNKCYVPQNLGEALDFRERQQSALDESN---TYQLPDGS 244

  Fly   248 VITIGNERFRCPEALFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANSVLSGGTTMYPGIAD 312
            .:.:...:...||..|.|.........|...:..|:..|::.:|..|.::.:..||.|:|||...
Human   245 RVELTPMQRVAPEMFFSPQVFEQPGPSIPRAIVESVESCEISLRPLLVSHVMACGGNTLYPGFTK 309

  Fly   313 RMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDE 365
            |:.:|:.....|:.|..:.....|.:|||:|.|::|.|||:|..|:|::||.|
Human   310 RLFRELMGDHVSSTKATVWEGSNRNFSVWLGASVVAHLSTYQSEWMSREEYGE 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act88F	NP_524367.1	ASKHA_NBD_actin	8..371	CDD:466823	125/376 (33%)
ACTL8	NP_110439.2	ACTIN	4..363	CDD:214592	125/377 (33%)