Protein Alignment Act88F and ACTR6

DIOPT Version :10

• Sequence 1: NP_524367.1
• Gene: Act88F / 41885
• FlyBaseID: FBgn0000047
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_071941.1
• Gene: ACTR6 / 64431
• HGNCID: 24025
• Length: 396
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 105/412 - (25%)
• Similarity: 190/412 - (46%)
• Gaps: 68/412 - (16%)

  Fly     9 LVIDNGSGMCKAGFAGDDA---PRAVFPSIVGRPRHQGVMVGMGQKDSYVG---DEAQSKRGILT 67
            ||:|||:...|.|::.::.   |...|.|...|.:            ::..   ||.:...|:..
Human     4 LVLDNGAYNAKIGYSHENVSVIPNCQFRSKTARLK------------TFTANQIDEIKDPSGLFY 56

  Fly    68 LKYPIEHGIITNWDDMEKIWHHTFYNEL-RVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSP 131
            : .|.:.|.:.|||...::|.:.|..|: :|...:..:::||...|..:.:|.|.:|:||.:.
Human    57 I-LPFQKGYLVNWDVQRQVWDYLFGKEMYQVDFLDTNIIITEPYFNFTSIQESMNEILFEEYQ-- 118

  Fly   132 AMYVAIQAVLSLYASGRTTG------------IVLDSGDGVSHTVPIYEGFALPHAILRLDLAGR 184
                 .||||.:.|...:..            |::|||...:|.||.........||:|:::.|:
Human   119 -----FQAVLRVNAGALSAHRYFRDNPSELCCIIVDSGYSFTHIVPYCRSKKKKEAIIRINVGGK 178

  Fly   185 DLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATA---AASTSLEKSYELPD- 245
            .||::|.:|::.|  ......|..::..:||.:|||:.||.::|..|   ....::...|.|||
Human   179 LLTNHLKEIISYR--QLHVMDETHVINQVKEDVCYVSQDFYRDMDIAKLKGEENTVMIDYVLPDF 241

  Fly   246 -----------------------GQVITIGNERFRCPEALFQPSFLGMESCGIHETVYNSIMKCD 287
                                   .|::.:.||||..||.||.||.:|::..||.|.:..||....
Human   242 STIKKGFCKPREEMVLSGKYKSGEQILRLANERFAVPEILFNPSDIGIQEMGIPEAIVYSIQNLP 306

  Fly   288 VDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLST 352
            .:::...:.|.||:||.:::||..||:..|:..|.|:...:.::.|.......|.||.:::....
Human   307 EEMQPHFFKNIVLTGGNSLFPGFRDRVYSEVRCLTPTDYDVSVVLPENPITYAWEGGKLISENDD 371

  Fly   353 FQQMWISKQEYDESGPGIVHRK 374
            |:.|.:::::|:|:|..:...|
Human   372 FEDMVVTREDYEENGHSVCEEK 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act88F	NP_524367.1	ASKHA_NBD_actin	8..371	CDD:466823	104/407 (26%)
ACTR6	NP_071941.1	ASKHA_NBD_Arp6	3..386	CDD:466816	103/403 (26%)