Protein Alignment Act88F and ACTA1

DIOPT Version :10

• Sequence 1: NP_524367.1
• Gene: Act88F / 41885
• FlyBaseID: FBgn0000047
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001091.1
• Gene: ACTA1 / 58
• HGNCID: 129
• Length: 377
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 349/377 - (92%)
• Similarity: 363/377 - (96%)
• Gaps: 1/377 - (0%)

  Fly     1 MCD-DDAGALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRG 64
            ||| |:..|||.|||||:.||||||||||||||||||||||||||||||||||||||||||||||
Human     1 MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRG 65

  Fly    65 ILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFN 129
            |||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||
Human    66 ILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFN 130

  Fly   130 SPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTDYLMKIL 194
            .||||||||||||||||||||||||||||||:|.||||||:||||||:|||||||||||||||||
Human   131 VPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL 195

  Fly   195 TERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCP 259
            |||||||.|||||||||||||||||||||||.||||||:|:||||||||||||||||||||||||
Human   196 TERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCP 260

  Fly   260 EALFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPS 324
            |.||||||:||||.|||||.||||||||:|||||||||:|:||||||||||||||||||||||||
Human   261 ETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPS 325

  Fly   325 TIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376
            |:||||||||||||||||||||||||||||||||:||||||:||.|||||||
Human   326 TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act88F	NP_524367.1	ASKHA_NBD_actin	8..371	CDD:466823	338/362 (93%)
ACTA1	NP_001091.1	ASKHA_NBD_actin	8..372	CDD:466823	338/363 (93%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	112..125		12/12 (100%)
		Interaction with alpha-actinin. /evidence=ECO:0000250|UniProtKB:P68135	360..372		8/11 (73%)