Protein Alignment Act88F and ACTRT2

DIOPT Version :10

• Sequence 1: NP_524367.1
• Gene: Act88F / 41885
• FlyBaseID: FBgn0000047
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_536356.3
• Gene: ACTRT2 / 140625
• HGNCID: 24026
• Length: 377
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 181/372 - (48%)
• Similarity: 253/372 - (68%)
• Gaps: 2/372 - (0%)

  Fly     5 DAGALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLK 69
            |:.|::.|||||.||||.:|:..||.:..||||..:.|.......||..:||:||..|:..|.|.
Human     8 DSPAVIFDNGSGFCKAGLSGEFGPRHMVSSIVGHLKFQAPSAEANQKKYFVGEEALYKQEALQLH 72

  Fly    70 YPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMY 134
            .|.|.|:||.|||:|::|.|.|..||.|.|.:.|:|.||..|||:.|||||.::|||.|..||.|
Human    73 SPFERGLITGWDDVERLWKHLFEWELGVKPSDQPLLATEPSLNPRENREKMAEVMFENFGVPAFY 137

  Fly   135 VAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTDYLMKILTERGY 199
            ::.||||:||||...||:|:||||.|:.||||:||::||||:.:|.:||||:|:.||::|...|:
Human   138 LSDQAVLALYASACVTGLVVDSGDAVTCTVPIFEGYSLPHAVTKLHVAGRDITELLMQLLLASGH 202

  Fly   200 SFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPEALFQ 264
            :|....::.:|.|||:|||||||:.|:|::........|  |:||||.:|::|:...:.|||||.
Human   203 TFPCQLDKGLVDDIKKKLCYVALEPEKELSRRPEEVLRE--YKLPDGNIISLGDPLHQAPEALFV 265

  Fly   265 PSFLGMESCGIHETVYNSIMKCDVDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPSTIKIK 329
            |..||.:|.|:...|.:||.|||.||:|.|:...|||||||::.|:.||:.||:..||.....||
Human   266 PQQLGSQSPGLSNMVSSSITKCDTDIQKILFGEIVLSGGTTLFHGLDDRLLKELEQLASKDTPIK 330

  Fly   330 IIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376
            |.|||:|.:|.|||.||:.|||:|:|||::..::.|.|..:|.|:||
Human   331 ITAPPDRWFSTWIGASIVTSLSSFKQMWVTAADFKEFGTSVVQRRCF 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act88F	NP_524367.1	ASKHA_NBD_actin	8..371	CDD:466823	176/362 (49%)
ACTRT2	NP_536356.3	ASKHA_NBD_actin_Arp-T1-3	10..368	CDD:466848	175/359 (49%)