DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6118 and mod(mdg4)

DIOPT Version :9

Sequence 1:	NP_001097806.1	Gene:	CG6118 / 41884	FlyBaseID:	FBgn0038339	Length:	967	Species:	Drosophila melanogaster
Sequence 2:	NP_788698.1	Gene:	mod(mdg4) / 49228	FlyBaseID:	FBgn0002781	Length:	610	Species:	Drosophila melanogaster

Alignment Length:	593	Identity:	124/593 - (20%)
Similarity:	200/593 - (33%)	Gaps:	199/593 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 DQYLLSWNNFHGNMCRGFHSLQKDEKMVDVTIAAGGKIFKAHKLVLSVCSPYFQQIFLENPS-SH 454
            :|:.|.||||:.|:..|||.......:|||::||.|:|.|||:||||||||:|:::|.:.|| :|
  Fly     5 EQFSLCWNNFNTNLSAGFHESLCRGDLVDVSLAAEGQIVKAHRLVLSVCSPFFRKMFTQMPSNTH 69

  Fly   455 PILLMADVEASHMAGLLDFMYSGQVNVKYEDLPVFLKVAEAMKIKGLHTEKNLDSDASDISSPHE 519
            .|:.:.:|..|.:..|:.|||.|:||||.:.||.|:..||:::||||     .|:|.
  Fly    70 AIVFLNNVSHSALKDLIQFMYCGEVNVKQDALPAFISTAESLQIKGL-----TDNDP-------- 121

  Fly   520 SDGTECRYERGTHSVNITSGHAAGYGGAPS-SQQSSPSPSLNGPNRCPTPLSSGGSGNPNYAGFR 583
                                       ||. .|:|||.|:                        .
  Fly   122 ---------------------------APQPPQESSPPPA------------------------A 135

  Fly   584 EHIKSKATLAETFMKNLNRNNNNNNSSNNYNHLGGSNGSLNLTEADSNSFAILQANSKKMLDSAR 648
            .|::.:...|:...                                                  |
  Fly   136 PHVQQQQIPAQRVQ--------------------------------------------------R 150

  Fly   649 KQHKYLAKRKILMHYNTELGGEKRLKEMERDRYPSAEQHDDALNNNHSHAQDNIMEPIITTIVPQ 713
            :|.:..|:.||                         |..||.|.:........:::   ||..||
  Fly   151 QQPRASARYKI-------------------------ETVDDGLGDEKQSTTQIVIQ---TTAAPQ 187

  Fly   714 TPPPSTHNNNFKIRLVESHHLTNNSNNNQNQSSNN----NNSSSSPQSNDCNNDEEALNLVQIPN 774
            .............:.::|..|...:.......|.|    ..||.:|.|:...        |:...
  Fly   188 ATIVQQQQPQQAAQQIQSQQLQTGTTTTATLVSTNKRSAQRSSLTPASSSAG--------VKRSK 244

  Fly   775 ANGSRN-----REATPTCATPTPDIQLIKREVKTELSPAENLSNNNGHDDEMAGAGFDRKYDDNN 834
            .:.|.|     ...|.|.||.|  .||:.:::..:.|....................:.:|.|
  Fly   245 TSTSANVMDPLDSTTETGATTT--AQLVPQQITVQTSVVSAAEAKLHQQSPQQVRQEEAEYID-- 305

  Fly   835 NNSGLDME--TDSNNNNSKPGGDNNNGLALALGKHKLLSAINRNIEQD-HPDHEHQDQQDREADH 896
                |.||  |.|..:.|:..||       |.|     .|....:|.| :.|..:.|....|.:.
  Fly   306 ----LPMELPTKSEPDYSEDHGD-------AAG-----DAEGTYVEDDTYGDMRYDDSYFTENED 354

  Fly   897 GGNNCNSDDN---------------NNNNHSQHLDLSTIKNIATAEILCGLKSKVLKLEEEQRER 946
            .||...::.:               .:.|:|:...:.|..:....|......:...|:...:|.|
  Fly   355 AGNQTAANTSGGGVTATTSKAVVKQQSQNYSESSFVDTSGDQGNTEAQAATSASATKIPPRKRGR 419

  Fly   947 ERERERER 954
            .:.:..::
  Fly   420 PKTKVEDQ 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6118	NP_001097806.1	Myb_DNA-bind_4	20..97	CDD:290549
		BTB	408..508	CDD:279045	46/100 (46%)
		BTB	419..510	CDD:197585	44/91 (48%)
mod(mdg4)	NP_788698.1	BTB	22..118	CDD:279045	46/100 (46%)
		BTB	33..118	CDD:197585	43/89 (48%)
		FLYWCH	452..512	CDD:282369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	63	1.000	Domainoid score	I10232
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.100