DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6118 and CG15812

DIOPT Version :9

Sequence 1:	NP_001097806.1	Gene:	CG6118 / 41884	FlyBaseID:	FBgn0038339	Length:	967	Species:	Drosophila melanogaster
Sequence 2:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	99/525 - (18%)
Similarity:	190/525 - (36%)	Gaps:	137/525 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 LSWNNFHGNMCRGFHSLQKDEKMVDVTIAA-GGKIFKAHKLVLSVCSPYFQQIFLENP-SSHPIL 457
            |.|......:.....||:.|.:..:|.:|: .|...:||..|||.||...:.:.::.| .....:
  Fly     4 LKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATI 68

  Fly   458 LMADVEASHMAGLLDFMYSGQVNVKYEDLPVFLKVAEAMKIKGLHTEKNLDSDASDISSPHESDG 522
            ::.|:....:..:|.|:|.|:.::....||.||   ||:.:.|:.:..:.:.:.|  :||...|.
  Fly    69 MLPDIRGDLLECMLSFIYMGETSLPSASLPEFL---EAINLLGIKSAISFECNPS--ASPPSVDV 128

  Fly   523 TECRYERGTHSVNITSGHA-AGYGGAPS---SQQSSPSPSLNGPNRCPTPLSSGGSGNPNYAG-F 582
            .       .||:.:.|..: .|...|.:   ..:..|.|.::    .|....:|....|:::. .
  Fly   129 E-------NHSLAVESAKSITGLQIAEAELLDDEEEPHPMVS----VPATTLAGSQHQPSHSSRS 182

  Fly   583 REHI----KSKATLAETFMKNLNRNNNNNNSSNNYNHLGGSNGSLNLTEADSNSFAILQA----- 638
            .|:|    ..|.|.:...|        :.:||.|...|..:.|:..:|:: ::|.:.::|
  Fly   183 LEYIDVYEPPKITYSIEHM--------DGSSSGNQFILTENTGTFTITQS-ASSLSKIEADETGT 238

  Fly   639 ----------------------NSKKMLDSARKQHKYLAKRKILMHYNTEL-------------- 667
                                  :..:|:|....|...|.:    :...||:
  Fly   239 SGAEVDLGDDDVDADLAEDSEEHESQMIDEEFAQADPLME----LEAGTEMDDDDDVHDQLVDEE 299

  Fly   668 ---------GGEKRL------KEMER--DRYPSAEQH--------DDALNNNHSHAQDNIM---- 703
                     ||:.|:      |.::|  |..|:..|.        .|.:|:....|.|.::
  Fly   300 IDDKPRKLGGGKTRIRRPISAKAVKRLSDCKPTRIQQFAALKREVKDDINDALDLAADAVIIEGL 364

  Fly   704 --------EPIITTIV---PQTPPPSTHNNNFKIRLVESHHLTNNSNNNQNQSSNNNNSSSSPQS 757
                    ..|..|::   .:|.|....||..:..|.|::....|.::.::.||......|:...
  Fly   365 SLQKAADRFDISKTVLWRRVRTNPAYMRNNRERPSLQEAYERLKNGHSLKSISSELQIPMSTLHR 429

  Fly   758 NDCNNDEEALNLVQIPNANGSRNREATPTCATPTPDIQLIKREVKTELSPAENLSNNNGHDDEMA 822
            :......:.    ::||....|.|:.||            |.|::.:|:.|.:...|.|.....|
  Fly   430 HKVRLSAQG----RLPNFVSCRKRDNTP------------KDELRDKLAKAVHACLNEGMSQNHA 478

  Fly   823 GAGFD 827
            ...|:
  Fly   479 ANLFE 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6118	NP_001097806.1	Myb_DNA-bind_4	20..97	CDD:290549
		BTB	408..508	CDD:279045	26/101 (26%)
		BTB	419..510	CDD:197585	23/92 (25%)
CG15812	NP_523897.2	BTB	20..113	CDD:279045	25/95 (26%)
		BTB	35..118	CDD:197585	21/85 (25%)
		HTH_psq	348..392	CDD:283007	7/43 (16%)
		HTH_psq	458..501	CDD:283007	6/26 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020