DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6118 and CG8924

DIOPT Version :9

Sequence 1:	NP_001097806.1	Gene:	CG6118 / 41884	FlyBaseID:	FBgn0038339	Length:	967	Species:	Drosophila melanogaster
Sequence 2:	NP_573091.1	Gene:	CG8924 / 32557	FlyBaseID:	FBgn0030710	Length:	514	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	95/483 - (19%)
Similarity:	179/483 - (37%)	Gaps:	157/483 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 QYLLSWNNFHGNMCRGFHSLQKDEKMVDVTIAAGGKIFKAHKLVLSVCSPYFQQIFLENPSSHPI 456
            ::.:.||:..|::...|..|...::.||||:|..|:....|:|||:.||.||:.|..|:|..||:
  Fly     7 EFCVRWNSHLGSIGAAFPQLLAGQRFVDVTLACEGQQVHCHRLVLAACSTYFEAILAEHPCKHPV 71

  Fly   457 LLM-ADVEASHMAGLLDFMYSGQVNVKYEDLPVFLKVAEAMKIKGLHTEKNLDSDASDISSPHES 520
            ::: .:::...:..|:||||.|:|||....|...|:.||.::|:||:
  Fly    72 IILPREIKLWEIQALVDFMYKGEVNVTQAGLGQLLRCAEQLQIRGLY------------------ 118

  Fly   521 DGTECRYERGTHSVNITSGHAAGYGGAPSSQQSSPSPSLNGPNRCPTPLSSGGSGNPNYAGFREH 585
             |:|                      ||.:.:.....||.            .:.:|
  Fly   119 -GSE----------------------APINYKKLQQASLE------------AAKDP-------- 140

  Fly   586 IKSKATLAETFMKNLNRNNNNNNSSNNYNHLGGSNGSLNLTEADSNSFAILQANSKKMLDSARKQ 650
               .||.|.:| |:::....::.::|       |..|..:|.:.:....:            ..|
  Fly   141 ---AATTARSF-KHVDSAETDDAATN-------STTSTTMTTSSAPPLPV------------NHQ 182

  Fly   651 HKYLAKRKILMHYNTELGGEKRLKEMERDRYPSAEQHDDALNNNHSHAQDNIME-PIITTIVPQT 714
            ...:.||                            |:.||........|..:.: |.|.....|.
  Fly   183 QPTVLKR----------------------------QNPDARQQQQQQQQQQVQQRPQINGSNAQQ 219

  Fly   715 PPPSTHNNNFKIRLVESHHLTNNSNNNQNQSSNNNNSSSSPQSNDCNNDEEAL-NLVQIPNANGS 778
            |..:|..|     ::.||......:::.::..||.|:... |.:|||...:|: |.:.:
  Fly   220 PSKATSTN-----VLGSHSNAPTEDDSGDEVPNNWNAYGE-QFDDCNISAQAVDNKMNV------ 272

  Fly   779 RNREATPTCATPTPDIQLIKREVKTELSPAENLSNNNGHDDEMAGAGFDRKYDDNNNNS------ 837
                          .:.|.:..::.:|...:.|.:|...|.....|     :|:||::|
  Fly   273 --------------HLSLQQARMQMQLQQQQYLDSNVEDDHNYVAA-----HDENNDSSFATGVP 318

  Fly   838 -----GLDMETDSNNNNSKPGGDNNNGL 860
                 .|.::||.:.:.:..||.:::.:
  Fly   319 CGSGLSLSLDTDLDTSANTSGGLSHSSI 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6118	NP_001097806.1	Myb_DNA-bind_4	20..97	CDD:290549
		BTB	408..508	CDD:279045	37/100 (37%)
		BTB	419..510	CDD:197585	34/91 (37%)
CG8924	NP_573091.1	BTB	25..117	CDD:279045	34/91 (37%)
		BTB	34..117	CDD:197585	32/82 (39%)
		MerR	378..407	CDD:278788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451910
Domainoid	1	1.000	68	1.000	Domainoid score	I9675
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.950