DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6118 and CG3726

DIOPT Version :9

Sequence 1:	NP_001097806.1	Gene:	CG6118 / 41884	FlyBaseID:	FBgn0038339	Length:	967	Species:	Drosophila melanogaster
Sequence 2:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster

Alignment Length:	560	Identity:	121/560 - (21%)
Similarity:	192/560 - (34%)	Gaps:	155/560 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 QYLLSWNNFHGNMCRGFHSLQKDEKMVDVTIAAGGKIFKAHKLVLSVCSPYFQQIFLENPSSH-- 454
            ||.|.|...|.|:...|..|.......|||:|..|::.:||::||..||.:|..: |.|.:|.
  Fly     5 QYCLRWKYHHSNLQTMFSQLLDRGCFCDVTLACEGQLIRAHRVVLCACSTFFDAV-LSNYASERD 68

  Fly   455 PILLMADVEASHMAGLLDFMYSGQVNVKYEDLPVFLKVAEAMKIKGLHTEKNLDSD--------A 511
            ||::|.||..:.:..|::|||.|::||::..||..||.|:.:|||||......|.:        |
  Fly    69 PIIIMKDVTFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKGLAEVTWRDDEDGPPPPMAA 133

  Fly   512 SDISSPHESDGTECRYERGTHSVNITSGHAAGYGGAPSSQQSSPSPSLNGPNRCPTPLSSGGSGN 576
            ::..||..|...       :::.::...|      ....||...:|.||
  Fly   134 AEFHSPPRSLAE-------SYAQDLILQH------QQQQQQGPAAPPLN---------------- 169

  Fly   577 PNYAGFREHIKSKATLAETFMKNLNRNNNNNNSSNNYNHLGGSNGSLNLTEADSNSFAILQANSK 641
                     :.|.|.|.|...:.....:....|......||.......||.| |.|..:...:..
  Fly   170 ---------LHSSAALLERDRERERERDRERLSPGMEGVLGRMPVMTPLTGA-SGSAGVGSVSGG 224

  Fly   642 KMLDSARKQHKYLAKRKILMHYNTELGGEKRLKEMERDRYPSAEQHDDALN--------NNHSHA 698
            ..|:.......:|              |.||    :|.|.|..:.: |..|        .|...|
  Fly   225 TSLEGVAPVEHFL--------------GPKR----KRGRPPLDDAY-DVFNVRKLAQYAANLEPA 270

  Fly   699 QDNIME---------PIITTIVPQTPPPST----HNNNFKIRLVESHHLTNNSNNNQNQ------ 744
            |...:|         |:.........||:.    .....:.:..:...|..:.:::|.|
  Fly   271 QRAYLETARHFTEEPPLAAHAASMASPPAACPPKQRQRLRHQQQQQQQLLQSESSDQEQPAAGQD 335

  Fly   745 -SSNNNNSSSSPQ---SNDCNNDEEALNLVQIPNANGSRNREATPTCATPTPDIQLIK----REV 801
             |:...|.|::|:   ..|.|..|         ...|..:..|..|.|:.:...:|.|    ||.
  Fly   336 WSNLEPNGSATPKLLSDGDANKQE---------TEGGDESLPAVLTTASSSGTKKLEKIGERRER 391

  Fly   802 KTELSPAENLSNNNGHD---------DEM-------------------------AGAGFDRKYDD 832
            ..:|..|..|...:|.|         ||:                         ..|.|..||:
  Fly   392 HGKLRHARRLYEKSGEDEVDPPKEEPDELPQPVEEIENEHLVANRAESPRPTVVIPASFACKYE- 455

  Fly   833 NNNNSGLDMETDSNNNNSKPGGDNNNGLALALGKHKLLSA 872
                .|:   |.:...:....|..:.|.:..:.:|.:|.|
  Fly   456 ----GGV---TAAGGGSGSGTGSGSLGSSYLINEHGMLMA 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6118	NP_001097806.1	Myb_DNA-bind_4	20..97	CDD:290549
		BTB	408..508	CDD:279045	39/101 (39%)
		BTB	419..510	CDD:197585	38/92 (41%)
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	39/97 (40%)
		BTB	32..121	CDD:197585	37/89 (42%)
		HTH_psq	587..622	CDD:283007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451911
Domainoid	1	1.000	63	1.000	Domainoid score	I10232
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.950