Protein Alignment Atx2 and PBP1

DIOPT Version :9

• Sequence 1: NP_732033.1
• Gene: Atx2 / 41883
• FlyBaseID: FBgn0041188
• Length: 1084
• Species: Drosophila melanogaster
• Sequence 2: NP_011694.3
• Gene: PBP1 / 853089
• SGDID: S000003410
• Length: 722
• Species: Saccharomyces cerevisiae
• Alignment Length: 718
• Identity: 157/718 - (21%)
• Similarity: 239/718 - (33%)
• Gaps: 252/718 - (35%)

  Fly    23 YNSNDNSLRPTNNKAGAGGG----NGGAAVRPSAQGVYNN-----------TFFMHSATALVGSV 72
            :...|:|   ||::.|....    |||...:.::...|.|           .:.:.::   :||.
Yeast     5 FRKRDSS---TNSRKGGNSDSNYTNGGVPNQNNSSMFYENPEITRNFDDRQDYLLANS---IGSD 63

  Fly    73 VEVRLRSGNIYEGVFRT----FSGNFDIALELPACIKS----------KNLPEEGKVPKHIIFPA 123
            |.|.:.||..|.|:..:    .:...|:.|..|....|          |.|.|.      ::...
Yeast    64 VTVTVTSGVKYTGLLVSCNLESTNGIDVVLRFPRVADSGVSDSVDDLAKTLGET------LLIHG 122

  Fly   124 DTVVTIVAKDFD-----------SQYATAG-----------------AFQTDGAISDKCNGARPD 160
            :.|..:..|:.|           :|..|..                 .|:||..||.  :|....
Yeast   123 EDVAELELKNIDLSLDEKWENSKAQETTPARTNIEKERVNGESNEVTKFRTDVDISG--SGREIK 185

  Fly   161 EKELEPW--DSGA-NGDID----IELDSAANGWDPNEMFRKNENTFGVTSTFDDSLASYTVPLDK 218
            |::||.|  :.|| :.||:    :|.|||:  ||   .|..||..|||.||||:.|  ||..::|
Yeast   186 ERKLEKWTPEEGAEHFDINKGKALEDDSAS--WD---QFAVNEKKFGVKSTFDEHL--YTTKINK 243

  Fly   219 GDSLEFKEAEAKAEKLAAEIENNPT------CRDR---LDLENGDEEALFAAVERPSTE------ 268
            .|. .:.:...:||::|.|||:..|      ..||   :|....|||.|::.|:|...|
Yeast   244 DDP-NYSKRLQEAERIAKEIESQGTSGNIHIAEDRGIIIDDSGLDEEDLYSGVDRRGDELLAALK 307

  Fly   269 --QDQRGDRGDR-------------------ERNDRDRER--------------EERDRDRDRDR 298
              .....::|:|                   ..|....|.              .|....:...:
Yeast   308 SNSKPNSNKGNRYVPPTLRQQPHHMDPAIISSSNSNKNENAVSTDTSTPAAAGAPEGKPPQKTSK 372

  Fly   299 GNKPRGAGDFQLRE---------------------------TMSSDRYITKQTRSITGPQLSHVG 336
            ..|...:.:.|:.|                           |:.|:..:..:..|.| |....|.
Yeast   373 NKKSLSSKEAQIEELKKFSEKFKVPYDIPKDMLEVLKRSSSTLKSNSSLPPKPISKT-PSAKTVS 436

  Fly   337 MSSQGSGRDRDTRGDGSMMMQSGGGSGQGGSTQSTAALMLAG-----GLKGVGPAPSANASADSS 396
            .::|.|....::|..||.:.|  |.|..|.:|:|:.:|....     |.|.    |..|   |:.
Yeast   437 PTTQISAGKSESRRSGSNISQ--GQSSTGHTTRSSTSLRRRNHGSFFGAKN----PHTN---DAK 492

  Fly   397 SKYSGGS---MVKRKTV----PQGGKVMRN-----------NVPTGGSNVSVS------------ 431
            ....|.|   .:|.|..    .:|.....|           ..||..:.:..|
Yeast   493 RVLFGKSFNMFIKSKEAHDEKKKGDDASENMEPFFIEKPYFTAPTWLNTIEESYKTFFPDEDTAI 557

  Fly   432 -------QGGNGNSVGQNKGGYQPSMGMPSQYSYQGNSQIMHGSSQYRNQSHMGGAN-----KLN 484
                   |....||:|....|..|:|||        |...|.|..       |||.:     .:|
Yeast   558 QEAQTRFQQRQLNSMGNAVPGMNPAMGM--------NMGGMMGFP-------MGGPSASPNPMMN 607

  Fly   485 GDSNANTNKPLP-QRQMRQYQGSQSNSSLNYGGEPQSLGKPVHGSHGGHPGQNSNSPPL----QT 544
            |.:..:....:| |.|...|..|.          ||.:  ||.||:|...|..:.||.:    ..
Yeast   608 GFAAGSMGMYMPFQPQPMFYHPSM----------PQMM--PVMGSNGAEEGGGNISPHVPAGFMA 660

  Fly   545 AGP 547
            |||
Yeast   661 AGP 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atx2	NP_732033.1	SM-ATX	61..128	CDD:291131	16/80 (20%)
PBP1	NP_011694.3	PBP1	3..722	CDD:227507	157/718 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343240
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5180
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001866
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12854
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2220
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960