DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6125 and AST56

DIOPT Version :9

Sequence 1:	NP_732032.1	Gene:	CG6125 / 41882	FlyBaseID:	FBgn0038337	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_565165.2	Gene:	AST56 / 844134	AraportID:	AT1G77990	Length:	677	Species:	Arabidopsis thaliana

Alignment Length:	581	Identity:	148/581 - (25%)
Similarity:	269/581 - (46%)	Gaps:	94/581 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 LSWITSYDREQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYVFFGTIPQVS 151
            |||...|.......||:||:||....|||||.||.||||..|||||::.:..:||...||..:::
plant    96 LSWGRQYKLNLFKKDLMAGLTLASLCIPQSIGYANLAGLDPEYGLYTSVVPPLIYSTMGTSRELA 160

  Fly   152 IGPTSLMAILTLQFCAD--KPV-------QVVIVLAFLAGLVELAMGVFQLGFIVSFIPAPVTKA 207
            |||.:::::|......|  .||       ::|..:.|.||..:...|:|:|||:|.|:.......
plant   161 IGPVAVVSLLLSSMVRDLQDPVTDPIAYRKIVFTVTFFAGAFQAIFGLFRLGFLVDFLSHAALVG 225

  Fly   208 FTSGTALIVVFAQIKNLLGVRIKGFPSIGDFFTN------------------IRPTDAAMGISCM 254
            |.:|.|:::...|:|.|.|:         ..|||                  .:|.:..:|.|.:
plant   226 FMAGAAIVIGLQQLKGLFGL---------THFTNKTDVVSVLSSVFHSLHHPWQPLNFVIGSSFL 281

  Fly   255 VVLLSLRLLSQVNFKQDTPVTRRLKKILWYISISRNALVVFFTGLLVFIWVKKSSIEAVPFALSS 319
            :.:|..|.:.           :|..|:.|..:::....||..| |:|:              ||:
plant   282 IFILLARFIG-----------KRNNKLFWIPAMAPLISVVLAT-LIVY--------------LSN 320

  Fly   320 KVSSAMPTIK--LPPFAFEYQNRTYVFTDILHELGSGIVVVPIVAVLANVAIAKAF--VKDGNLD 380
            ..|..:..:|  .|.|.....|:....:..|.::....::..|:|:...:|:.::|  :|...||
plant   321 AESRGVKIVKHIKPGFNQLSVNQLQFKSPHLGQIAKIGLISAIIALTEAIAVGRSFATIKGYRLD 385

  Fly   381 ASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGLIVLSALSILTPYFQYI 445
            .::||:.:|..|||||..|.....|:|:|:||:.::|..|.::.|...:.|:.:|.:||.:..:.
plant   386 GNKEMMAMGFMNIAGSLSSCYVATGSFSRTAVNFSAGCETVVSNIVMAITVMISLEVLTRFLYFT 450

  Fly   446 PKASLSAVLIAAVIFMIDLAPVKELWQTNKKDFFSWVGSFIICLVAGVELGLLFGIVLSMVFILL 510
            |.|.|::::::|:..:||::....:|:.:|.||...:.:|...|.|.||:|||..:.:|...|:|
plant   451 PTAILASIILSALPGLIDVSGALHIWKLDKLDFLVLIAAFFGVLFASVEIGLLLAVGISFARIML 515

  Fly   511 RLGNPKFEVTLKQHESTYY--VHIVPQSD--------------VYYTGVDALRSELRGACR---- 555
            ....|..|...:..::..:  ::..|.::              :.:...:.:|..:..:.:
plant   516 SSIRPSIEALGRLSKTDIFGDINQYPMANKTAGLLTLRISSPLLCFANANFIRDRILNSVQEIEG 580

  Fly   556 -------LYHNDFPVV-LDCARFMQFDATFSEMLISVAKEMASHDVLLILQNMSLKVQQML 608
                   |..|...|| ||.:..|..|.:....|..:.:|:||:|:.|::.:...:|...|
plant   581 EENEQEVLKENGLQVVILDMSCVMGVDTSGVFALEELHQELASNDIRLVIASPRWRVLHKL 641

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	sulP	87..620	CDD:273284	148/581 (25%)
		HCO3_cotransp	108..462	CDD:304903	102/384 (27%)
		STAS	530..608	CDD:294402	17/103 (17%)
AST56	NP_565165.2	sulP	94..662	CDD:273284	148/581 (25%)
AST56	NP_565165.2	STAS	540..662	CDD:279997	18/102 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		mtm1058
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.980