DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6125 and slc26a6l

DIOPT Version :9

Sequence 1:	NP_732032.1	Gene:	CG6125 / 41882	FlyBaseID:	FBgn0038337	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001107889.1	Gene:	slc26a6l / 559448	ZFINID:	ZDB-GENE-080220-10	Length:	808	Species:	Danio rerio

Alignment Length:	509	Identity:	130/509 - (25%)
Similarity:	244/509 - (47%)	Gaps:	79/509 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 SKPKEAHWLVRRIFFLSWITSYD-REQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAF 135
            |.|:....:|..:..|||:..|. .:....|||:||::|:..:||.:|||.||.|...:|||::.
Zfish    47 SVPRIKRSIVGFLPVLSWLPRYSIWDYGMPDLISGISVGIMHLPQGMAYALLASLPPVFGLYTSL 111

  Fly   136 IGSIIYVFFGTIPQVSIGPTSLMAIL----TLQFCADKP----------------------VQVV 174
            ..|:||..|||...:|:|..::::|:    |.:...|..                      |||.
Zfish   112 YPSLIYFIFGTSRHISVGTFTILSIMIGSVTERLAPDTDFLIYNGTNVTGEVDIASRDLYRVQVA 176

  Fly   175 IVLAFLAGLVELAMGVFQLGFIVSFIPAPVTKAFTSGTALIVVFAQIKNLLGVRIKGFP------ 233
            .....|.||:::.:|:.|.||:.:::..|:.:.:|:..:...|.||:|.:|||..|.|.
Zfish   177 AAATVLGGLIQVVLGLVQFGFVGTYLSEPLVRGYTTAASAHAVVAQLKYILGVSPKRFNGPLSIV 241

  Fly   234 -SIGDFFTNI----RPTDAAMGISCMVVLLSLRLLSQVNFKQDTPVTRRLKKILWYISISRNALV 293
             ::.|.||.:    .||..|..:|.:|::.:..|.:.:..|...|:...|..|:....||
Zfish   242 YTLVDLFTLLPETHLPTLVASVVSIVVLITAKELNNALKKKMIIPIPVELCTIVVATVIS----- 301

  Fly   294 VFFTGLLVFIWVKKSSIEAVPFALSSKVSSAMPTIKLPPFAFEYQNRTYVFTDILHELGSGIVVV 358
             |:|.|          .|:...::...:.|.:....:|        ..|:|::::.:    ...:
Zfish   302 -FYTRL----------NESYKISVVGDIPSGLQPPSVP--------NVYIFSEVVLD----AFAM 343

  Fly   359 PIVAVLANVAIAKAF-VKDG-NLDASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTP 421
            .||....::::.|.| :|.| .::::||::.|||.|..|.||.....|.:.:||.:.:::|.:|.
Zfish   344 AIVGYAISISLGKTFALKHGYKVESNQELVALGLSNTVGGFFQCFSVCSSMSRSLIQESTGGKTQ 408

  Fly   422 MAGIYTGLIVLSALSILTPYFQYIPKASLSAVLIAAVIFMI-DLAPVKELWQTNKKDFFSWVGSF 485
            :||:.:|:|||..:..|...||.:|||.|||::...:..|. ....:..||::||.|...|:.:|
Zfish   409 IAGVVSGVIVLVTVLKLGSLFQELPKAVLSAIVFVNLKGMFKQYYDIVTLWRSNKIDLLIWLVTF 473

  Fly   486 IICLVAGVELGLLFGIVLSMVFILLRLGNPKFEVTLKQHESTYYVHIVPQSDVY 539
            :..::..:::||...:..:::.::.|...|.:  .|..|        :|.:::|
Zfish   474 VSTVLFNLDMGLGASMGFALLTVIFRTQRPSY--ALLGH--------LPGTELY 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	sulP	87..620	CDD:273284	127/494 (26%)
		HCO3_cotransp	108..462	CDD:304903	102/392 (26%)
		STAS	530..608	CDD:294402	2/10 (20%)
slc26a6l	NP_001107889.1	Sulfate_transp	77..472	CDD:279284	114/422 (27%)
		HCO3_cotransp	<338..449	CDD:304903	35/114 (31%)
		STAS_SulP_like_sulfate_transporter	<710..777	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810