DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6125 and CG9717

DIOPT Version :9

Sequence 1:	NP_732032.1	Gene:	CG6125 / 41882	FlyBaseID:	FBgn0038337	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster

Alignment Length:	583	Identity:	201/583 - (34%)
Similarity:	323/583 - (55%)	Gaps:	42/583 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LVRRIFFLSWITSYDREQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYVFF 144
            |.:|...|.|:..|.::..|.|::|||::.||:|||::|||.:|||..:||||:.|:|..||:|.
  Fly    69 LYKRFPILVWLPQYKKDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQYGLYACFLGCFIYIFI 133

  Fly   145 GTIPQVSIGPTSLMAILTLQFCADKPVQVVIVLAFLAGLVELAMGVFQLGFIVSFIPAPVTKAFT 209
            |:...|.||||::.|:|:.|. |....|:..:|.||.||:|:.||||:|||::.|:..||...||
  Fly   134 GSSKDVPIGPTAISALLSFQI-AGGSWQIATLLTFLTGLIEILMGVFRLGFLIDFVSGPVGAGFT 197

  Fly   210 SGTALIVVFAQIKNLLGVRIKG------FPSIGDFFTNIRPTDAAMGISCMVVLLSLRLLSQVNF 268
            |..:||:..:|:|:.||::..|      :.||.:...||...|..:||.|:.:|||||.|:....
  Fly   198 SAVSLIIFSSQMKDFLGIKTSGNTFLQVWISIVNDIHNISWPDFILGIVCITLLLSLRALASCTL 262

  Fly   269 ---KQDTPVTRRLKKILWYISISRNALVVFFT---GLLVFIWVKKSSIEAVPFALSSKVSSAMPT 327
               :..|...:.|..|.|.|..:||||:|..|   |..:|:..|::.::.|.|     |...:|:
  Fly   263 GPKEGKTTAQKLLTGIFWTIGTARNALLVCGTAGLGYWLFVNGKENLVKTVGF-----VPKGLPS 322

  Fly   328 IKLPPFAF---------EYQNRTYVFTDILHELGSGIVVVPIVAVLANVAIAKAFVKDGNLDASQ 383
            .:.|||..         |.......|.|::..||||::|||::|:|..:|:.:||......||:|
  Fly   323 FQPPPFHMDAVVNETTGEVLQEAQSFWDMVSTLGSGLIVVPLIALLETMAVVQAFADGKPTDATQ 387

  Fly   384 EMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGLIVLSALSILTPYFQYIPKA 448
            |::..|:||:|.||...:.:.|...|.|:..||||||.::.:||.:||:.||..|||.|.|||||
  Fly   388 ELIASGVCNVANSFVQGLRSNGGIARGAILNASGVRTQLSNLYTSVIVIIALLYLTPCFYYIPKA 452

  Fly   449 SLSAVLIAAVIFMIDLAPVKELWQTNKKDFFSWVGSFIICLVAGVELGLLFGIVLSMVFILLRLG 513
            :|::::|||||||:....:|.:|.:.|.|....:|:|..|||..::||:|.||.:::||||.:..
  Fly   453 ALASIIIAAVIFMVQYRVIKPMWHSKKTDLIPGLGAFFACLVLPLQLGILVGIGINVVFILYQAA 517

  Fly   514 NPKFEV-TLKQHESTYYVHIVPQSDVYYTGVDALRSELRGACRLYHNDFPVVLDCARFMQFDATF 577
            .||..: ||.......|:.:.|...:.:..::.:|..:....:  .:..|||:||......|.|.
  Fly   518 RPKLRIETLATTTGLKYLMLTPDRCLIFPSMEFVRKVINKQGQ--KSTLPVVIDCTHIYGADFTA 580

  Fly   578 SEMLISVAKEMASHDVLLILQNMSLKVQQMLPVMGNVRFCQEDSQLSSHLQVEKEAPVVEAKL 640
            ::::.::..:....:..|...|:..:|.|:.            ..|:..|.|..:...:.|||
  Fly   581 AKVISTMVMDFKLREQPLFFYNLQPRVAQVF------------EGLNKDLVVIYDINTLHAKL 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	sulP	87..620	CDD:273284	193/554 (35%)
		HCO3_cotransp	108..462	CDD:304903	148/374 (40%)
		STAS	530..608	CDD:294402	13/77 (17%)
CG9717	NP_651812.1	sulP	74..607	CDD:273284	191/540 (35%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	14/91 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439014
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm51364
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	10	9.900