DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6125 and CG9702

DIOPT Version :9

Sequence 1:	NP_732032.1	Gene:	CG6125 / 41882	FlyBaseID:	FBgn0038337	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster

Alignment Length:	609	Identity:	204/609 - (33%)
Similarity:	335/609 - (55%)	Gaps:	61/609 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 ASKYSKPKEA------------HWLVRRIFFLSWITSYDREQAFADLIAGITLGLTIIPQSIAYA 120
            |||.||..|:            ..|::|:.||:|:..|:|:....|||||.|:|||:|||.:||:
  Fly    50 ASKESKNPESCCSRYARNIFRKKTLLKRLPFLTWLPHYNRQDCIGDLIAGFTVGLTVIPQGLAYS 114

  Fly   121 ALAGLSSEYGLYSAFIGSIIYVFFGTIPQVSIGPTSLMAILTLQFCADKPVQVVIVLAFLAGLVE 185
            .:.||..|||||.:|:|..:||..||....:||.|::.:::|.|| |....|..::|.||.|::|
  Fly   115 GVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQF-AQGSWQRSVLLTFLTGIIE 178

  Fly   186 LAMGVFQLGFIVSFIPAPVTKAFTSGTALIVVFAQIKNLLGVRIKGFPSIGDFFT---------- 240
            :.|.:|:||.:|.|:..||:..|||..||||..:|::::|||:..|    |.|..
  Fly   179 ILMAIFKLGCLVEFVSGPVSAGFTSAVALIVSTSQMRSMLGVKSDG----GSFLATWISMFRDIE 239

  Fly   241 NIRPTDAAMGISCMVVLLSLRLLSQVNF-----KQDTPVTRRLKKILWYISISRNA-LVVFFTGL 299
            |:|..|..:|..|:::||::|.|.:...     .:.....|.:..::.::|.|||| :|:.||.:
  Fly   240 NVRVADTCLGFGCVILLLAMRSLGKFTIGPKDESRRNGFQRVVNTVIKFLSTSRNASVVILFTAV 304

  Fly   300 LVFIWVKKSSIEAVPFALSSKVSSAMPTIKLPPFAFEYQ--NRT--------YVFTDILHELGSG 354
            .:::....::    ||.|:..:...|||..||||:.|.|  |.|        ..|.:::..||.|
  Fly   305 TMYLDANGTN----PFRLTGNIPKGMPTPSLPPFSIEPQPGNETAGIPAVEGQTFPEMVQSLGYG 365

  Fly   355 IVVVPIVAVLANVAIAKAFVKDGNLDASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVR 419
            :|:||::|:|..:::.|||.|...:|.:|||:..|:.|||.|.||.....|...||||:.|||.|
  Fly   366 LVIVPLMALLETMSVCKAFAKGKQIDITQEMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCR 430

  Fly   420 TPMAGIYTGLIVLSALSILTPYFQYIPKASLSAVLIAAVIFMIDLAPVKELWQTNKKDFFSWVGS 484
            |.|:.:|.|:||:.||:.||.|..:||||.|:|::|:||||.:....|..:|::.:.|....:.:
  Fly   431 TNMSNLYIGVIVVLALNFLTEYIAFIPKAVLAAIIISAVIFQVQYQVVTPMWRSKRSDLVPGILA 495

  Fly   485 FIICLVAGVELGLLFGIVLSMVFILLRLGNPKFEVTLKQHESTY---YVHIVPQSDVYYTGVDAL 546
            |:.|||..:|:|::..|.::::|||.....||  |||:|.|:..   :|.|.|...:.:..|:.:
  Fly   496 FVTCLVLPLEIGIMVAIGVNLLFILYYAARPK--VTLEQLETQQGIRFVKITPDRCLIFPSVEFV 558

  Fly   547 RSEL--RGACRLYHNDFPVVLDCARFMQFDATFSEMLISVAKEMASHDVLLILQNMSLKVQQMLP 609
            |:.:  .|:    .:..|||:||......|.|.::::.|:..:.......:|..|:...|..:..
  Fly   559 RNMVLKLGS----KSTLPVVIDCTYIYAADFTAAKVISSIVDDFRRRQQKIIFFNLKPSVVSVFE 619

  Fly   610 VMGNVR--FCQEDSQLSSHLQVEK 631
            .: |.|  .|.....|:..|:.::
  Fly   620 GL-NTRLVLCYNTHALNQELRPDE 642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	sulP	87..620	CDD:273284	193/565 (34%)
		HCO3_cotransp	108..462	CDD:304903	143/379 (38%)
		STAS	530..608	CDD:294402	17/79 (22%)
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	192/556 (35%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	19/91 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439020
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	1	0.950	-	0	Normalized mean entropy	S3380
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm51364
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	11	10.850