Protein Alignment CG6125 and SLC26A11

DIOPT Version :9

• Sequence 1: NP_732032.1
• Gene: CG6125 / 41882
• FlyBaseID: FBgn0038337
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_016879994.1
• Gene: SLC26A11 / 284129
• HGNCID: 14471
• Length: 696
• Species: Homo sapiens
• Alignment Length: 682
• Identity: 218/682 - (31%)
• Similarity: 352/682 - (51%)
• Gaps: 80/682 - (11%)

  Fly    13 PKRNGRNRSSGEATGGQPQATVATIYDPGCEEKEKYTAQNGDDYYGQAHTVDLDVASKYSKPKEA 77
            |.|.....|.|.:.|...:...|:...|..|.....||      .|||.:....:|........|
Human    36 PPRPVPGDSCGPSCGDARRPQAASPSGPTVEMPSSVTA------LGQARSSGPGMAPSACCCSPA 94

  Fly    78 HWLVRRIFFLSWITSYDREQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYV 142
            . |.||:..|:|:.||..:....|.:||:::|||.|||::|||.:|||..:|||||||:|..:|.
Human    95 A-LQRRLPILAWLPSYSLQWLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFMGCFVYF 158

  Fly   143 FFGTIPQVSIGPTSLMAILTLQFCADKPVQVVIVLAFLAGLVELAMGVFQL-------------- 193
            |.||...|::|||::|::|...:...:|...|: ||||:|.::|||||.:|
Human   159 FLGTSRDVTLGPTAIMSLLVSFYTFHEPAYAVL-LAFLSGCIQLAMGVLRLAHISPHPLGLGGAG 222

  Fly   194 ----------GFIVSFIPAPVTKAFTSGTALIVVFAQIKNLLGVRIKGFPSIGDFFTNI------ 242
                      ||::.||..||.|.|||..|:.:.|.|||||||  ::..|.  .||..:
Human   223 TSSMSPLGWPGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLG--LQNIPR--PFFLQVYHTFLR 283

  Fly   243 ----RPTDAAMGISCMVVLLSLRLLSQ----VNFKQDTPVTRRLKKILWYISISRNALVVFFTGL 299
                |..||.:|:.||::||.|:|:..    |: .:..|..|..:.::|..:.:||||||.|..|
Human   284 IAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVH-PEMPPGVRLSRGLVWAATTARNALVVSFAAL 347

  Fly   300 LVFIWVKKSSIEAV---PFALSSKVSSAMPTIKLPPFAFEYQNRTYVFTDILHELGSGIVVVPIV 361
            :.:      |.|..   ||.|:.:.:..:|.:::|||:....|.|..||:::.::|:|:.|||::
Human   348 VAY------SFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLM 406

  Fly   362 AVLANVAIAKAFVKDGN--LDASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAG 424
            .:|.::|:||||....|  :||:||:|.:||.|:.||..|:.|..|:|.|:||:..|||.||..|
Human   407 GLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGG 471

  Fly   425 IYTGLIVLSALSILTPYFQYIPKASLSAVLIAAVIFMIDLAPVKELWQTNKKDFFSWVGSFIICL 489
            :.||::||.:|..||..|.||||::|:||:|.||..:.|....:.||:..:.|......:|::|.
Human   472 LVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFDTKIFRTLWRVKRLDLLPLCVTFLLCF 536

  Fly   490 VAGVELGLLFGIVLSMVFILLRLGNPKFEVTLKQHESTYYVHIVPQSDVYYTGVDALRSELRGAC 554
            .. |:.|:|.|.::|::.:|.....|:.:|:    |....| :.|.|.:.:..::|||.|:....
Human   537 WE-VQYGILAGALVSLLMLLHSAARPETKVS----EGPVLV-LQPASGLSFPAMEALREEILSRA 595

  Fly   555 RLYHNDFPVVLDCARFMQFDATFSEMLISVAKEMASHDVLLILQNMSLKVQQMLPVMGNVRFCQE 619
            ........:||:|......|.|....|..:.::.....|.|....:.:.|.::| :..:::..|.
Human   596 LEVSPPRCLVLECTHVCSIDYTVVLGLGELLQDFQKQGVALAFVGLQVPVLRVL-LSADLKGFQY 659

  Fly   620 DSQL---SSHLQVE--------KEAPVVEAKL 640
            .|.|   ..||:.|        :|..:::.|:
Human   660 FSTLEEAEKHLRQEPGTQPYNIREDSILDQKV 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	sulP	87..620	CDD:273284	193/575 (34%)
		HCO3_cotransp	108..462	CDD:304903	153/396 (39%)
		STAS	530..608	CDD:294402	16/77 (21%)
SLC26A11	XP_016879994.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141499
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.820