Protein Alignment CG6125 and SLC26A11

DIOPT Version :10

• Sequence 1: NP_732032.1
• Gene: CG6125 / 41882
• FlyBaseID: FBgn0038337
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_006721896.1
• Gene: SLC26A11 / 284129
• HGNCID: 14471
• Length: 630
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 203/615 - (33%)
• Similarity: 332/615 - (53%)
• Gaps: 73/615 - (11%)

  Fly    80 LVRRIFFLSWITSYDREQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYVFF 144
            |.||:..|:|:.||..:....|.:||:::|||.|||::|||.:|||..:|||||||:|..:|.|.
Human    30 LQRRLPILAWLPSYSLQWLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFL 94

  Fly   145 GTIPQVSIGPTSLMAILTLQFCADKPVQVVIVLAFLAGLVELAMGVFQL---------------- 193
            ||...|::|||::|::|...:...:|...|: ||||:|.::|||||.:|
Human    95 GTSRDVTLGPTAIMSLLVSFYTFHEPAYAVL-LAFLSGCIQLAMGVLRLAHISPHPLGLGGAGTS 158

  Fly   194 --------GFIVSFIPAPVTKAFTSGTALIVVFAQIKNLLGVRIKGFPSIGDFFTNI-------- 242
                    ||::.||..||.|.|||..|:.:.|.|||||||  ::..|.  .||..:
Human   159 SMSPLGWPGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLG--LQNIPR--PFFLQVYHTFLRIA 219

  Fly   243 --RPTDAAMGISCMVVLLSLRLLSQ----VNFKQDTPVTRRLKKILWYISISRNALVVFFTGLLV 301
              |..||.:|:.||::||.|:|:..    |: .:..|..|..:.::|..:.:||||||.|..|:.
Human   220 ETRVGDAVLGLVCMLLLLVLKLMRDHVPPVH-PEMPPGVRLSRGLVWAATTARNALVVSFAALVA 283

  Fly   302 FIWVKKSSIEAV---PFALSSKVSSAMPTIKLPPFAFEYQNRTYVFTDILHELGSGIVVVPIVAV 363
            :      |.|..   ||.|:.:.:..:|.:::|||:....|.|..||:::.::|:|:.|||::.:
Human   284 Y------SFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGL 342

  Fly   364 LANVAIAKAFVKDGN--LDASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIY 426
            |.::|:||||....|  :||:||:|.:||.|:.||..|:.|..|:|.|:||:..|||.||..|:.
Human   343 LESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLV 407

  Fly   427 TGLIVLSALSILTPYFQYIPKASLSAVLIAAVIFMIDLAPVKELWQTNKKDFFSWVGSFIICLVA 491
            ||::||.:|..||..|.||||::|:||:|.||..:.|....:.||:..:.|......:|::|...
Human   408 TGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFDTKIFRTLWRVKRLDLLPLCVTFLLCFWE 472

  Fly   492 GVELGLLFGIVLSMVFILLRLGNPKFEVTLKQHESTYYVHIVPQSDVYYTGVDALRSELRGACRL 556
             |:.|:|.|.::|::.:|.....|:.:|:    |....| :.|.|.:.:..::|||.|:......
Human   473 -VQYGILAGALVSLLMLLHSAARPETKVS----EGPVLV-LQPASGLSFPAMEALREEILSRALE 531

  Fly   557 YHNDFPVVLDCARFMQFDATFSEMLISVAKEMASHDVLLILQNMSLKVQQMLPVMGNVRFCQEDS 621
            ......:||:|......|.|....|..:.::.....|.|....:.:.|.::| :..:::..|..|
Human   532 VSPPRCLVLECTHVCSIDYTVVLGLGELLQDFQKQGVALAFVGLQVPVLRVL-LSADLKGFQYFS 595

  Fly   622 QL---SSHLQVE--------KEAPVVEAKL 640
            .|   ..||:.|        :|..:::.|:
Human   596 TLEEAEKHLRQEPGTQPYNIREDSILDQKV 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	PRK11660	87..620	CDD:481320	193/575 (34%)
SLC26A11	XP_006721896.1	SUL1	42..608	CDD:440424	195/584 (33%)