DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6125 and Slc26a10

DIOPT Version :9

Sequence 1:	NP_732032.1	Gene:	CG6125 / 41882	FlyBaseID:	FBgn0038337	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_006513627.1	Gene:	Slc26a10 / 216441	MGIID:	2143920	Length:	693	Species:	Mus musculus

Alignment Length:	480	Identity:	121/480 - (25%)
Similarity:	226/480 - (47%)	Gaps:	65/480 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 ASKYSKPKEAHWLVRRIFFLSWITSYD-REQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGL 131
            ||..|.|.....|:.|:..|.|:..|. |.....|.:||:|:|:..:||.:|:|.|..:...:||
Mouse    74 ASACSGPGAWRVLLARLPPLRWLPQYRWRAWLLGDAVAGVTVGVVHVPQGMAFALLTSVPPVFGL 138

  Fly   132 YSAFIGSIIYVFFGTIPQVSIGPTSLMAILT---LQFCADKP-----------------VQVVIV 176
            |::|...:||...||...:|.|..::::::|   ::....:|                 |.....
Mouse   139 YTSFFPVLIYSLLGTGRHLSTGTFAVLSLMTGSVVERVVPEPLAGNLSGIEREQLEARRVGAAAA 203

  Fly   177 LAFLAGLVELAMGVFQLGFIVSFIPAPVTKAFTSGTALIVVFAQIKNLLGVRI----------KG 231
            :||.:|.:.|.|.|.|||.:.:|:..||.||.|||.||.|:.:|:.:|||:.:          |.
Mouse   204 VAFGSGALMLGMFVLQLGVLSTFLSEPVIKALTSGAALHVLVSQLPSLLGLSLPRQIGCFSLFKT 268

  Fly   232 FPSIGDFFTNIRPTDAAMGISCMVVLLSLRLLSQVNFKQD--TPVTRRLKKILWYISISRNALVV 294
            ..::....:...|.:..:....:|:|:.::.|: |.|:..  ||:...:..:|.       |.|:
Mouse   269 LAAVLSALSQSSPAEVTISALSLVLLVPVKELN-VRFRDRLLTPIPGEVVMVLL-------ATVL 325

  Fly   295 FFTGLLVFIWVKKSSIEAVPFALSSKVSSAMPTIKLPPFAFEYQNRTYVFTDILHELGSGIVVVP 359
            .||..|    ..:.:::.|     ..:....|...||..            |.|..:.:..:.:.
Mouse   326 CFTSSL----DTRYNVQVV-----GPLPGGFPQPLLPTL------------DELPRILADSLPIS 369

  Fly   360 IVAVLANVAIAKAFVK--DGNLDASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPM 422
            :|....:.::|..:..  ...::.:||:|..|:.|:..|.||..|.......:::...:|..|.:
Mouse   370 LVTFAVSTSLASIYADKYSYTIEPNQELLAHGVSNLISSLFSCFPNSATLATTSLLVDAGGNTQL 434

  Fly   423 AGIYTGLIVLSALSILTPYFQYIPKASLSAVLIAAVIFM-IDLAPVKELWQTNKKDFFSWVGSFI 486
            ||:::..:||:||..|.|:|.|:|||.|:.:.|:::..| ..:..:.:||..:..||..|:.:::
Mouse   435 AGLFSCAVVLAALLWLRPFFYYLPKAVLACINISSMRQMFFQMQELPQLWHISHVDFAVWIVTWV 499

  Fly   487 ICLVAGVELGLLFGIVLSMVFILLR 511
            ..:...|:|||..|:|:||:.::.|
Mouse   500 AVVTLNVDLGLAVGVVVSMMTVVCR 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	sulP	87..620	CDD:273284	115/461 (25%)
		HCO3_cotransp	108..462	CDD:304903	93/388 (24%)
		STAS	530..608	CDD:294402
Slc26a10	XP_006513627.1	sulP	91..670	CDD:273284	115/463 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910